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Search / Trial NCT05537363

Agility Training and Its Relations in Elderly Adults With and Without MCI

Launched by NATIONAL TAIWAN UNIVERSITY HOSPITAL · Sep 11, 2022

Trial Information

Current as of August 19, 2025

Not yet recruiting

Keywords

Aging Agility Training Cognition Function Fall Mild Cognitive Impairment Motor Function

ClinConnect Summary

This clinical trial is studying the effects of agility training on older adults, both those with mild cognitive impairment (MCI) and those who are healthy. The goal is to see how agility training can help improve physical abilities, thinking skills, and reduce the risk of falls in elderly individuals. The trial is divided into three parts. In the first part, researchers will assess agility and its relationship to cognitive and motor functions in different groups of participants, including healthy young adults, healthy elderly adults, and elderly adults with MCI.

To participate, individuals must be over 65 years old, able to walk independently for more than 30 meters, and have certain cognitive test scores indicating they do not have severe cognitive impairment. The trial includes various tests to measure agility, cognitive abilities, motor skills, and brain activity. In the second and third parts, participants will be involved in either agility training or a control group that receives health education, with sessions twice a week for eight weeks. After the training, participants will be followed up at different intervals to see how they are doing. This trial aims to understand better how specific training can enhance the quality of life for elderly individuals.

Gender

ALL

Eligibility criteria

  • Part 1:
  • Inclusion Criteria:
  • 1. has a score of ≥ 24 on the Mini-Mental State Examination (MMSE)
  • 2. able to walk independently for more than 30 meters without assistive aids
  • 3. able to follow orders
  • Exclusion Criteria:
  • 1. poorly-controlled or unstable systematic disease
  • 2. has a history of central nervous system disease
  • 3. currently taking antidepressants, anti-anxiety, or other psychiatric drugs that may affect blood flow in the brain
  • 4. subjects with achromatopsia
  • Part 2:
  • Inclusion Criteria:
  • 1. older than 65 years old
  • 2. score of Mini-Mental State Examination (MMSE) ≥ 24 and score of Montreal Cognitive Assessment (MoCA) ≤ 26
  • 3. able to walk independently for more than 30 meters without assistive aids
  • 4. able to follow orders
  • Exclusion Criteria:
  • 1. poorly controlled or unstable systematic disease
  • 2. has a history of central nervous system disease
  • 3. currently taking antidepressants, anti-anxiety, or other psychiatric drugs that may affect blood flow in the brain
  • 4. has other medical conditions for which exercise is contraindicated
  • 5. subjects with achromatopsia
  • Part 3:
  • Inclusion Criteria:
  • 1. older than 65 years old
  • 2. score of Mini-Mental State Examination (MMSE) ≥ 24
  • 3. able to walk independently for more than 30 meters without assistive aids
  • 4. able to follow orders
  • Exclusion Criteria:
  • 1. poorly controlled or unstable systematic disease
  • 2. has a history of central nervous system disease
  • 3. currently taking antidepressants, anti-anxiety, or other psychiatric drugs that may affect blood flow in the brain
  • 4. has other medical conditions for which exercise is contraindicated
  • 5. subjects with achromatopsia

About National Taiwan University Hospital

National Taiwan University Hospital (NTUH) is a leading medical institution renowned for its commitment to advancing healthcare through innovative research and clinical trials. As a pioneer in medical education and patient care in Taiwan, NTUH integrates cutting-edge technology with comprehensive clinical expertise to facilitate groundbreaking studies across various medical fields. The hospital’s dedicated research team collaborates with local and international partners to enhance the understanding of diseases and improve treatment outcomes. By prioritizing patient safety and ethical standards, NTUH strives to contribute to the global medical community and foster advancements in healthcare practices.

Locations

Patients applied

0 patients applied

Trial Officials

Yan Ci Liu, PhD

Principal Investigator

National Taiwan University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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