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Search / Trial NCT05539391

Optimisation Strategy for Emergency Tracheal Intubation

Launched by UNIVERSITY HOSPITAL, BORDEAUX · Sep 13, 2022

Trial Information

Current as of July 25, 2025

Recruiting

Keywords

Out Of Hospital Intubation Complications Vital Distress Rapid Sequence Intubation Rocuronium Gum Elastic Bougie

ClinConnect Summary

This clinical trial is studying a new approach to help patients who need emergency tracheal intubation, which is a procedure used to open the airway in critical situations. The researchers want to see if using a combination of techniques—such as a muscle relaxant called rocuronium, using a bag mask to help with breathing before the intubation, and a special tool called a Gum Elastic Bougie—can reduce complications related to the intubation process. The goal is to improve the safety and effectiveness of this life-saving procedure for patients in distress.

To participate in this trial, patients must be at least 18 years old and experiencing severe health issues that require emergency intubation, such as difficulty breathing, trauma, or altered consciousness. However, patients who are in cardiac arrest or have certain medical conditions that prevent them from using the muscle relaxant or bag mask will not be eligible. If you or someone you know qualifies, you can expect to receive care from experienced medical professionals who will follow this new strategy to ensure the best possible outcomes during this critical procedure.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Patient adult (≥ 18 years) presenting with vital distress requiring emergency tracheal intubation as assessed by the emergency physician in the out-of-hospital setting.
  • Patient with all conditions (trauma, dyspnea, coma, overdoses, and shock) except those in cardiac arrest will be included.
  • Exclusion Criteria:
  • Patient presenting of a contraindication to succinylcholine, and/or rocuronium, and/or sugammadex (rocunorium antagonist).
  • Patient who have contraindication to bag face mask ventilation before intubation (ongoing emesis, hematemesis, or hemoptysis).
  • Patient that are not members of a medical aid scheme (beneficiary or main member).
  • Patient under specific protection measures: pregnant, parturient or nursing women; legal protection or deprived of liberty: patient under judicial protection, patient under guardianship/curatorship.

About University Hospital, Bordeaux

The University Hospital of Bordeaux is a leading academic medical center dedicated to advancing healthcare through innovative research and clinical excellence. As a prominent sponsor of clinical trials, the institution integrates cutting-edge scientific inquiry with patient care, fostering an environment that encourages collaboration among multidisciplinary teams. With a commitment to improving treatment outcomes and enhancing patient safety, the University Hospital of Bordeaux plays a pivotal role in the development of new therapies and medical technologies, contributing significantly to the global medical community.

Locations

Angers, , France

Bordeaux, , France

Poitiers, , France

Bordeaux, , France

Toulouse, , France

Lyon, , France

Melun, , France

Garches, , France

Beaumont Sur Oise, , France

Bobigny, , France

Cergy Pontoise, , France

Créteil, , France

Eaubonne, , France

La Tronche, , France

Montpellier, , France

Nantes, , France

Paris, , France

Paris, , France

Paris, , France

Saint Denis, , France

Saint Pierre, , France

Patients applied

0 patients applied

Trial Officials

Xavier COMBES, Pr

Principal Investigator

Université Hospital, Bordeaux

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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