Voice Rest and Injection Laryngoplasty

Launched by UNIVERSITY OF VIRGINIA · Sep 12, 2022

Keywords

ClinConnect Summary

This clinical trial is looking at how resting your voice after receiving an injection to help with vocal cord paralysis affects your voice quality and breathing. The study aims to find out if taking a break from speaking can improve outcomes compared to patients who continue to use their voice as normal after the procedure.

To participate, you need to be over 18 years old and plan to have an injection to enhance your vocal cords for reasons like weakness or immobility. However, if you’ve had recent radiation treatment for head and neck issues, are undergoing chemotherapy, or have certain other medical conditions, you won’t be eligible to join. If you take part in the trial, you’ll be monitored to see how well your voice improves with or without voice rest after the procedure. This could help doctors understand the best ways to support patients with vocal cord problems in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Age \>18 years old
• 2. Undergoing injection augmentation by Dr. McGarey, Dr. Torrecillas, or Dr. Daniero for the following conditions:
• • 1. Glottic insufficiency from atrophy, scar, or presbylarynx
• • 2. Unilateral or bilateral vocal fold immobility
• • 3. Unilateral or bilateral vocal fold hypomobility
• Exclusion Criteria:
• • 1. Prior history of head and neck radiation.
• • 2. Active or recent (within 3 months) chemotherapy.
• • 3. Age \<18 years old
• • 4. Incarcerated individuals will be excluded due to inability to enroll in post-intervention clinic visit
• • 5. Presence of posterior glottic stenosis
• • 6. Presence of acute laryngeal injury
• • 7. Bedside inpatient injection augmentation
• • 8. Vocal fold Injection with steroids or cidofovir