Cognitive-Behavioral Therapy and Exercise Training in Adolescents At-Risk for Type 2 Diabetes

Launched by COLORADO STATE UNIVERSITY · Sep 13, 2022

Keywords

ClinConnect Summary

This clinical trial is looking at ways to help prevent type 2 diabetes in teenage girls who may be at risk. The study will explore whether participating in a group that focuses on cognitive-behavioral therapy (which helps improve mood and handle stress) or joining an exercise training group can reduce stress, boost physical activity, improve fitness, and lower insulin resistance. Some girls will also take part in both the therapy and exercise groups to see if that combination is more effective.

To participate, girls need to be between 12 and 17 years old, have a higher body weight for their age, and have a family history of type 2 diabetes. They should also have some symptoms of depression. However, girls with certain medical conditions or those taking specific medications that affect mood, weight, or insulin levels cannot join. If eligible, participants can expect to engage in supportive activities that promote mental well-being and physical health, all while helping researchers learn more about preventing diabetes in young women.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Female
• • Age 12-17 years
• • Body Mass Index (BMI)\>= 85 for age and sex
• • Type 2 Diabetes (T2D) first-or second-degree relative
• • Center for Epidemiologic Studies Depression Scale (CES-D) total score \>=21
• Exclusion Criteria:
• • T2D/ Type 1 Diabetes (T1D) or any major medical condition (e.g. cardiovascular, renal) that would prohibit the ability to participate in exercise training
• • Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-5) conduct disorder, substance abuse/ dependence, obsessive compulsive disorder, panic attacks, post-traumatic stress disorder, anorexia/bulimia, \& schizophrenia
• • Insulin sensitizers, weight loss medications \& chronic steroids
• • Structured weight loss treatment or bariatric surgery
• • Pregnancy, nursing