A Study of Paravertebral Block in Thoracic Outlet Syndrome

Launched by MAYO CLINIC · Sep 14, 2022

Keywords

ClinConnect Summary

This study is looking at pain control for people with thoracic outlet syndrome who are having surgery to remove the first rib. It compares two ways of giving a nerve block (a local anesthetic shot near the spine) using ropivacaine: one group gets the block only before surgery, and the other group gets a block before surgery plus another block on the first day after surgery. Researchers will watch how pain changes after surgery using a 0–100 scale, as well as how recovery and daily functioning improve over the first two weeks. They’ll also track how long people stay in the hospital (about one day is typical).

If you’re considering joining, you would be an adult (18 or older) with thoracic outlet syndrome and scheduled for first rib surgery. You would not be pregnant, and you must not have had a first rib surgery on the same side, or have conditions like complex regional pain syndrome, a brachial plexus disorder, or a cervical rib. Participants are randomly assigned to one of the two block strategies, with both groups receiving ropivacaine blocks. The study is being run by Mayo Clinic in Florida, and it is currently enrolling by invitation, with results and completion expected around 2026. Trial number: NCT05544721.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • - All Thoracic Outlet Syndrome patients scheduled for first rib resection surgery.
• Exclusion Criteria:
• • Patients who are pregnant.
• • Patients with prior first rib resection on side of presentation.
• • Patients with complex regional pain syndrome (CRPS).
• • Patients with brachial plexus disorder.
• • Patients with cervical rib.