A Clinical Study of Transaxillary Endoscopic and Open Thyroidectomy for PTC

Launched by NANFANG HOSPITAL, SOUTHERN MEDICAL UNIVERSITY · Sep 15, 2022

Keywords

ClinConnect Summary

This clinical trial is looking at two different surgical methods for treating papillary thyroid cancer (PTC). Specifically, it aims to see how safe and effective a newer approach called gasless transaxillary endoscopic thyroidectomy is, compared to the standard open thyroidectomy. Both surgeries involve removing part of the thyroid gland and nearby lymph nodes, but the endoscopic method is less invasive and may allow for a quicker recovery.

To participate in this study, you need to be between 18 and 70 years old, have a confirmed diagnosis of papillary thyroid cancer, and meet certain health criteria. The researchers will provide more information about what to expect during the trial, including any potential risks and benefits. It's important to know that not everyone will qualify, especially if you have certain medical conditions or a history of specific health issues. Overall, the goal of this trial is to improve treatment options for patients with thyroid cancer.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • The patient's informed consent;
• • 18 years old \< age \< 70 years old;
• • Papillary thyroid carcinoma (Bethesda grade V-VI) was pathologically diagnosed by fine needle aspiration biopsy of the primary thyroid tumor before surgery;
• • Color Doppler TI-RADS 4c-5 of primary thyroid tumor;
• • The preoperative clinical staging is T1, N0-1a, M0 (see diagnostic criteria for details; according to AJCC-8th TNM tumor staging);
• • It is expected that R0 surgical results can be obtained by performing single thyroid lobectomy and isthmus resection + ipsilateral central lymph node dissection;
• • Preoperative ASA score I-III.
• Exclusion Criteria:
• • Pregnant or lactating patients;
• • Suffering from serious mental illness;
• • Preoperative imaging examinations suggest that the tumor is located in the thyroid isthmus or involves bilateral lobes;
• • Preoperative imaging examinations suggest the possibility of cervical lateral lymph node or distant metastasis;
• • Hashimoto's thyroiditis combined with hyperthyroidism or abnormal thyroid function;
• • History of neck surgery;
• • History of thyroid surgery (including ablation therapy for thyroid nodules);
• • Family history of thyroid cancer;
• • History of childhood ionizing radiation exposure;
• • History of other malignant diseases within 5 years;
• • A history of unstable angina or myocardial infarction within 6 months;
• • History of cerebral infarction or cerebral hemorrhage within 6 months;
• • History of continuous systemic corticosteroid therapy within 1 month;
• • Concurrent surgical treatment of other diseases is required;
• • Patients who are judged by the investigator to be unsuitable to participate in this trial.