Hydroxylated Polymethoxy Flavones Solid Dispersion in Treatment of Periodontitis

Launched by ASSIUT UNIVERSITY · Sep 15, 2022

Keywords

ClinConnect Summary

This clinical trial is studying a new treatment for periodontitis, which is a serious gum infection that can harm your gums and the bones supporting your teeth. The treatment being tested involves a special formulation of natural substances found in orange peels, designed to reduce inflammation and fight bacteria. These substances, called hydroxylated polymethoxy flavones, are usually difficult for the body to absorb, so researchers have created a gel that helps deliver them more effectively after a cleaning procedure for the gums.

To participate in this trial, you need to be between 18 and 65 years old and have been diagnosed with early stages of periodontitis (stage I or II). You should also be healthy overall, meaning you don't have conditions like diabetes or high blood pressure, and you should be a non-smoker without habits that could harm your teeth. If you qualify, you can expect to receive the new gel treatment and help researchers learn more about its effectiveness in managing periodontitis. This trial is currently not recruiting participants yet, but it could offer a new option for those struggling with gum disease in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients with periodontitis stage I-II
• • free from any systemic disorders.
• • no mobility - non-smokers - no parafunctional habits.
• • Each patient with minimum three periodontitis sites ( split-mouth study)
• Exclusion Criteria:
• • Smokers.
• • patients with diabetes, and hypertension.