El Sendero: Pathways to Health Study

Launched by UNIVERSITY OF SOUTHERN CALIFORNIA · Sep 20, 2022

Keywords

ClinConnect Summary

This project will continue our work in two birth cohorts of mother-infant Latino dyads (NCT04434027 \& NCT03141346) through a series of new assessments at age 6y, with a focus on examining the role of early nutritional exposures, exposures to environmental toxins, and social determinants of health (SDOH) on adiposity, eating behaviors, brain structure and function, cognitive outcomes, and chronic disease risk. This collection of assessments at 6 years of age is funded by two grants (R01 DK110793 01A1 \& P50 MD017344). Breast milk has been shown to contain certain macronutrients (human milk ...

Gender

ALL

Eligibility criteria

• • All participants will be recruited from two existing cohorts: The Effects of Natural Sugars in Breast Milk on Healthy Infant Growth and Development (NCT04434027) and Improving the Eating Habits of Mother and Her Infant Via Sugar Reduction (MAMITA) (NCT03141346). Children and their mother's will be eligible for this study at child 6 years of age.
• Initial Inclusion Criteria:
• • Mother's normal weight or overweight/obesity prior to pregnancy
• • Mother's who self identify as Hispanic
• • Mother's who are first-time moms
• • Mother's who have or have had singleton births
• • Mothers must be able/willing to understand the procedures of the study, and must be able to read English or Spanish at a 5th grade level
• Initial Exclusion Criteria:
• • Physician diagnosis of a major medical illness (including type 1 or type 2 diabetes) or eating disorder in mothers
• • Physical, mental, or cognitive issues that prevent participation
• • Chronic use of any medication that may affect body weight or composition, insulin resistance, or lipid profiles
• • Current smoking (more than 1 cigarette in the past week) or use of other recreational drugs
• • Clinical diagnosis of gestational diabetes
• • Pre-term/low birth weight infants, or diagnosis of any fetal abnormalities
• • Mothers less than 18 years of age at the time of delivery will not be eligible as to avoid potential confounding from those subjects who might still be completing adolescent growth