Micro-doses of Physical Activity for COPD

Launched by UNIVERSITY OF BRITISH COLUMBIA · Sep 20, 2022

Keywords

ClinConnect Summary

This clinical trial is studying how short breaks of walking can help improve blood vessel health in people with Chronic Obstructive Pulmonary Disease (COPD). COPD is a lung disease that makes it difficult to breathe, and many people with this condition tend to sit for long periods, which can increase the risk of heart problems. The researchers want to find out if taking a 5-minute walk every hour, instead of sitting still for 3 hours, can keep blood vessels healthier.

To join the study, participants need to be non-smokers with moderate to severe COPD who have not had any flare-ups in the past six weeks. They should not be doing structured exercise programs or have certain health conditions like heart disease or diabetes that could interfere with the study. If eligible, participants can expect to learn more about their health while helping researchers understand how small amounts of physical activity can make a difference. This study is currently recruiting participants, and both men and women of various ages can take part.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Non-smoking (\>6 months) patients with stable moderate-to-severe COPD (post bronchodilator forced expired volume in 1 sec/forced vital capacity\<0.7 and \<lower limit of normal, 30%\<Forced Expired Volume in 1 sec\<80% predicted and exacerbation free for \>6 weeks) will be recruited for the study.
• Exclusion Criteria:
• • 1. performing structured exercise training (or pulmonary rehabilitation)
• • 2. have a history of deep vein thrombosis
• • 3. are on anticoagulant medication
• • 4. have advanced cardiac or cerebrovascular disease (i.e. heart failure, previous stroke or myocardial infarction)
• • 5. have diabetes
• • 6. have musculoskeletal contraindications that limit their ability to perform physical activity
• • 7. vascular ultrasound measurements cannot be obtained.