Diabetic Foot Ulcers Microbiome and Pathogen Identification

Launched by UNIVERSITY OF MICHIGAN · Sep 22, 2022

Keywords

ClinConnect Summary

This clinical trial is studying how the bacteria and other tiny organisms living in diabetic foot ulcers affect healing and the risk of infection. People with diabetes often have slower healing wounds, which can lead to serious problems, including infections that might require amputation. By understanding the microbiome—essentially the community of microorganisms in these wounds—researchers hope to learn more about how to prevent infections and improve healing for patients with diabetic foot ulcers.

To participate in this study, you must have diabetes and a specific type of foot wound called a diabetic foot ulcer. You should also have a recent hemoglobin A1c level of 12% or less, which helps indicate how well your diabetes is being managed. Participants will need to be available for the entire study and agree to follow all procedures. However, individuals who are pregnant, have uncontrolled blood sugar, or currently have a COVID-19 infection are not eligible. If you join the study, you can expect to contribute to important research that could lead to better treatments and prevention strategies for diabetic foot ulcers in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • DFU patients with diabetes mellitus
• • Have a hemoglobin A1c\[HbA1c\] of 12% or less as measured within the last 6 months
• • Stated willingness to comply with all study procedures and availability for the duration of the study
• Exclusion Criteria:
• • Pregnant or lactating
• • Uncontrolled blood glucose as demonstrated by by a HbA1c of greater than 12%
• • Bilateral wound or ulcer
• • Current infection of Coronavirus (COVID-19)
• • Unable to provide informed consent or are unwilling to participate.