Potassium Containing Salt-Substitute in Hemodialysis-Dependent End Stage Kidney Disease

Launched by NYU LANGONE HEALTH · Sep 23, 2022

Keywords

ClinConnect Summary

This clinical trial is looking at the effects of a potassium-containing salt substitute in people with end-stage kidney disease who are on hemodialysis, which is a treatment that helps filter waste from the blood. Sixteen participants will take a potassium salt substitute for 16 days and then standard table salt for another 16 days, with a break in between. The researchers will measure potassium levels and other health indicators throughout the study to see how the salt substitute affects their potassium levels and overall well-being.

To participate, individuals must be at least 21 years old, currently receiving outpatient hemodialysis, and have a negative pregnancy test if they are women of childbearing age. Some people may not be eligible, such as those who have severe potassium levels, certain health conditions, or who have not been regularly attending their hemodialysis sessions. If you decide to join this trial, you can expect to provide information about your diet and health during the study, and you will be closely monitored by the research team.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Receiving outpatient maintenance HD therapy.
• • 2. Age ≥ 21 years.
• • 3. Negative serum pregnancy test for women of child-bearing capacity. Childbearing capacity will be defined by report of menstruation within ≤ 6 months.
• Exclusion Criteria:
• • 1. Currently incarcerated.
• • 2. Insufficient capacity for informed consent.
• • 3. Non-hemolyzed serum potassium concentration \>6.0 mEq/L within ≤30 days.
• • 4. Unscheduled HD for hyperkalemia within ≤30 days.
• • 5. Attendance at ≤10 of last 13 scheduled OP HD sessions.
• • 6. Co-habiting family member with known hyperkalemia.
• • 7. Co-habiting family with ≥stage 3b chronic kidney disease or chronic kidney disease of unknown severity.
• • 8. Hemoglobin \< 8.0 mg/dL.
• • 9. Use of other potassium supplements.