Central Neuromuscular Dysfunction in Patellofemoral Pain
Launched by HACETTEPE UNIVERSITY · Sep 29, 2022
Trial Information
Current as of June 27, 2025
Enrolling by invitation
Keywords
ClinConnect Summary
Patellofemoral joint problems constitute a significant portion of knee pain and injuries. Among these problems, patellofemoral pain, which is not directly related to an obvious structural abnormality such as ligament rupture, cartilage degeneration or tendinopathy, is characterized by pain in the retro or peri-patellar region, especially during activities such as squatting, running, and climbing stairs. It is a musculoskeletal disorder with a poor long-term prognosis despite treatment and education. In individuals with patellofemoral pain, disturbances in the function of the M. quadriceps f...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- Inclusion Criteria for Study Group:
- • 1. Volunteer to participate in the study,
- • 2. Be between the ages of 18 and 40,
- • 3. Having been diagnosed with patellofemoral pain,
- • 4. Unilateral or bilateral non-traumatic anterior knee pain provoked by at least 2 activities such as prolonged sitting, climbing stairs, squatting, running for at least the last 3 months,
- • 5. At least 3/10 pain descriptions during activities according to the Numerical Pain Scale,
- • 6. Pain on palpation in medial and lateral patellar facets and positive patellar grinding test.
- Inclusion Criteria for Control Group :
- • 1. Demographic characteristics (age and gender) similar to the study group
- • 2. Not having any diagnosis related to the knee joint
- Exclusion Criteria:
- • 1. Having any additional pathology (meniscal, ligamentous or tendinous problems) concerning the knee joint,
- • 2. Having a history of surgery involving the knee,
- • 3. Having a neuromuscular and/or metabolic disease,
- • 4. Having an additional pathology involving the lumbar spine and/or lower extremity,
- • 5. Presence of any disease affecting lower extremity circulation, foot pronation deformities pathologies, congenital patella subluxation/dislocation
- • 6. Having a history of deep vein thrombosis and peripheral vascular disease,
- • 7. Presence of endothelial dysfunction,
- • 8. Presence of diseases that will cause endothelial dysfunction (Hypertension, cardiovascular diseases, neurological diseases, systemic inflammation, obesity, diabetes, atherosclerosis, advanced age.), I. Presence of active infection
- • j. Being a cancer patient.
About Hacettepe University
Hacettepe University is a leading research institution in Turkey, renowned for its commitment to advancing medical science and healthcare through innovative clinical research. With a strong emphasis on interdisciplinary collaboration, the university supports a wide range of clinical trials aimed at improving patient outcomes and developing new therapeutic approaches. Hacettepe University is dedicated to maintaining the highest ethical standards and regulatory compliance in its research endeavors, fostering an environment that promotes scientific excellence and contributes to the global body of medical knowledge.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Ankara, , Turkey
Patients applied
Trial Officials
Cansu Gevrek Aslan, M.Sc.
Principal Investigator
Ankara Medipol Universty
Gizem I Kınıklı, Assoc. Prof.
Study Chair
Hacettepe Universty
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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