Lifestyle Interventions for the Treatment of Early Onset Alzheimer's Disease Study

Launched by INDIANA UNIVERSITY · Oct 5, 2022

Keywords

ClinConnect Summary

This clinical trial is exploring how certain lifestyle activities, like computerized brain training and Tai Chi-Qi Gong, can help people with early-onset Alzheimer's disease. Researchers want to see if these activities can improve thinking skills, daily functioning, and mood in participants compared to those who are not doing the training.

To join the study, participants should be between 40 and 64 years old, fluent in English, and in good health without other serious neurological conditions. They also need to be part of a larger study on early-onset Alzheimer's and have a support person who can help them. Participants can expect to engage in training sessions and assessments related to their cognitive health. It's important to note that having regular internet access for at least four hours a week is required to participate. This study aims to gather valuable information that could lead to new ways to support individuals with early-onset Alzheimer's disease.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Enrolled in the Longitudinal Early-Onset AD Study (LEADS) parent study, and being classified via LEADS consensus criteria as having amyloid-positive Early Onset Alzheimer's Disease
• • Aged 40-64 years at the time of enrollment into LEADS
• • Fluent in English
• • In good general health and absent another neurological disorder
• • Have a knowledgeable informant.
• • Have had a Clinical Dementia Rating scale of 0.5 to 1.0 at the time of enrollment into LEADS
• • Have sufficient vision, hearing, comprehension, and manual dexterity to participate in the testing and training program
• Exclusion Criteria:
• • • Have access to the internet (e.g., home, family, public library, etc.) for less than 4 hours per week