Correlation Between Postprandial Hypotension and Post-induction Hypotension in the Elderly.

Launched by PEKING UNION MEDICAL COLLEGE HOSPITAL · Oct 7, 2022

Keywords

ClinConnect Summary

This clinical trial is studying two conditions that can affect older adults: postprandial hypotension (PPH), which is a drop in blood pressure after eating, and post-induction hypotension (PIH), which can happen during surgery after anesthesia is given. The researchers want to understand how these conditions are related and how they might lead to complications during and after surgery for elderly patients.

To participate in this study, you need to be at least 65 years old and scheduled for a non-heart-related surgery that requires general anesthesia. The study is looking for patients who are generally healthy but may have certain medical conditions. If you decide to join, you'll help researchers learn more about how these blood pressure changes occur in older adults, which could improve care and outcomes for future patients. Your participation would involve monitoring your blood pressure during specific times related to eating and surgery, and the study is currently seeking volunteers.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Elderly patients (≥ 65 years old）;
• • 2. Patients with American Society of Anesthesiologists(ASA) grade I-III;
• • 3. Patients scheduled to undergo elective non-cardiac surgery under general anesthesia, with an anticipated surgical duration of over 1 hour；
• • 4. Patients with intra-tracheal intubation following intravenous general ；anesthesia induction and maintenance；
• Exclusion Criteria:
• • 1. Patients with vascular diseases such as aortic aneurysm, aortic dissection, symptomatic atherosclerotic obliterans, Buerger's disease, and Raynaud's syndrome
• • 2. Patients with secondary hypertension, including renal hypertension and endocrine hypertension.
• • 3. Patients with chronic kidney disease requiring dietary restrictions or dialysis.
• • 4. Patients with Parkinson's disease or other conditions causing tremors.
• • 5. Patients with problems related to oral food ingestion or those requiring enteral nutrition.
• • 6. Patients with difficulties in measuring the upper extremities or communication problems that would interfere with study procedures.
• • 7. Patients unable to remain in a supine position for at least 2 hours.