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Search / Trial NCT05577663

Guided Bone Regeneration in Alveolar Socket

Launched by ARISTOTLE UNIVERSITY OF THESSALONIKI · Oct 10, 2022

Trial Information

Current as of July 26, 2025

Recruiting

Keywords

Socket Seal Randomized Controlled Clinical Trial Alveolar Ridge Preservation Polylactic Glycolic Acid Membrane Free Gingival Graft Spontaneous Healing

ClinConnect Summary

This clinical trial is studying different ways to help preserve the bone in the jaw after a tooth is taken out. When a tooth is extracted, the bone around the area can shrink, which may make it harder to place dental implants later on. The researchers want to find out which method works best to keep the bone stable during healing. They will compare three different approaches: one where the extraction site is simply sutured closed, another where a small piece of tissue is added to help with healing, and a third where a special membrane is placed over the site.

To participate in this study, you need to be between 18 and 75 years old and have a single tooth that needs to be removed, with some remaining support from the surrounding bone. However, if you have certain health issues, are pregnant, or need multiple teeth removed, you may not be eligible. If you join, you’ll have some check-ups after the tooth extraction to see how well the area is healing over the next three months. This is an important step in improving dental care and ensuring better outcomes for future dental implants.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Referrals for a single tooth extraction
  • Periodontal destruction less than 50% of tooth support
  • Signed inform consent form
  • Exclusion Criteria:
  • Systematic diseases, contradicting surgical procedures and compromise wound healing (i.e. uncontrolled diabetes)
  • Medication that interferes with bone metabolism
  • Pregnancy or lactation
  • Multiple extractions
  • Absence of adjacent teeth
  • Loss of buccal bone, either due to periodontal disease or because of traumatic extraction

About Aristotle University Of Thessaloniki

Aristotle University of Thessaloniki (AUTH) is a prestigious institution in Greece, renowned for its commitment to advancing knowledge and innovation in the field of clinical research. As a leading academic sponsor of clinical trials, AUTH leverages its extensive resources and expertise to conduct rigorous studies that contribute to the understanding of various medical conditions and the development of novel therapeutic interventions. The university fosters collaboration among multidisciplinary teams, ensuring adherence to the highest ethical standards and regulatory requirements while promoting scientific excellence and enhancing patient care.

Locations

Thessaloniki, , Greece

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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