TOward a comPrehensive Supportive Care Intervention for Older Men With Metastatic Prostate Cancer

Launched by UNIVERSITY HEALTH NETWORK, TORONTO · Oct 12, 2022

Keywords

ClinConnect Summary

The TOward a comPrehensive Supportive Care Intervention for Older Men With Metastatic Prostate Cancer trial, also known as TOPCOP3, is studying how different types of supportive care can help older men with advanced prostate cancer. This includes evaluating a thorough health check-up and ongoing symptom monitoring over the phone. The goal is to see which approach works best, whether it's one of these methods, both, or neither, to improve the care of patients. The results will help researchers design larger studies in the future.

To participate, men must be at least 65 years old, have recently started or switched their cancer treatment, and be able to speak and understand English. They also need to have a working phone and be able to give their consent to join the study. Participants can expect to receive support and monitoring throughout the trial, which will help researchers learn more about the best ways to care for older men facing this challenging disease. It’s important to note that this study is currently recruiting participants, and it has strong backing from cancer support groups.

Gender

MALE

Eligibility criteria

• Inclusion Criteria:
• • 1. Starting an ARAT or started an ARAT within 2 weeks prior to being approached or switching ARATs due to progression or toxicity
• • 2. Diagnosed with mPC (castration-sensitive or resistant) or nmCRPC (non-metastatic castration-resistant prostate cancer)
• • 3. At least 65 years old
• • 4. Able to provide written informed consent
• • 5. Has a working telephone
• Exclusion Criteria:
• • 1. Unable to speak English (as contact with the nurse interventionist is via phone, not all outcome measures are available in multiple languages)
• • 2. Major neuropsychiatric abnormalities (severe depression or moderate-severe dementia)
• • 3. Life expectancy \<3 months as estimated by the oncologist