Allergy and Immunology Natural History Study

Launched by COLUMBIA UNIVERSITY · Oct 14, 2022

Keywords

ClinConnect Summary

The Allergy and Immunology Natural History Study is looking into certain genetic diseases that affect our immune system and cause allergic reactions or inflammation. The goal of this study is to better understand these conditions by examining blood and other samples from participants and some of their family members. If you or a family member are suspected of having an inherited immune issue, such as an allergic inflammation disorder, you might be eligible to participate.

Eligible participants can range from newborns to individuals who are 99 years old, and there’s no restriction based on gender, race, or disability. If you join the study, you’ll be asked to provide samples like blood and possibly other tissues, which will be used for future research to help doctors learn more about these complex conditions. It’s important to note that individuals with certain acquired immune system issues may not be included in the study. Overall, this research aims to deepen our understanding of immune health and could lead to better treatments in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Subjects, ages birth to 99 years old, known to have or suspected of having an inherited disorder of allergic inflammation, or mast cell homeostasis, or activation or immune dysregulation.
• • Blood relatives of enrolled subjects will be eligible for enrollment.
• • There will be no discrimination as to age, gender, race, or disability.
• • Subjects/guardians must be willing and able to give informed consent.
• • Subjects must agree to have their blood stored for future studies of the immune system and/or other medical conditions.
• Exclusion Criteria:
• • • The presence of an acquired abnormality of the immune system, such as cytotoxic chemotherapy or malignancy may be grounds for possible exclusion if, in the opinion of the investigator, the presence of such a disease process would interfere with evaluation.