Microbiome-Directed Food for Sustained Recovery From Acute Malnutrition

Launched by INSTITUT DE RECHERCHE EN SCIENCES DE LA SANTE, BURKINA FASO · Oct 14, 2022

Keywords

ClinConnect Summary

This clinical trial is testing a new type of food called microbiome-directed food (MDF) to help treat acute malnutrition in children aged 6 to 23 months. The main goal is to find out if this new food can help children recover from malnutrition better than the standard treatments they currently receive. Specifically, the researchers want to see if children eating MDF will recover faster and stay healthy longer compared to those receiving other types of ready-to-use foods designed for malnutrition.

To participate in this trial, children must be between 6 and 23 months old and have either moderate or severe malnutrition. Some signs of malnutrition include being underweight for their age or having a lower arm circumference than normal. However, children with certain health issues or allergies will not be eligible for this study. Families who join the trial can expect their child to receive the new food for treatment and be monitored for their progress. This study is important as it aims to improve recovery rates for children suffering from malnutrition, which is a significant health concern in many communities.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age between 6 and 23 months
• • Moderate wasting: WHZ \< -2 and ≥ -3 or MUAC \< 125 mm and ≥ 115mm or - Severe wasting: WHZ \< -3 or MUAC \< 115 mm
• Exclusion Criteria:
• • Bilateral pitting edema
• • Not eating/lack of appetite
• • Current illness medical complications requiring inpatient treatment
• • Presence of any congenital abnormality or underlying chronic disease that may affect growth or risk of infection
• • Known contraindication/hypersensitivity/allergy to MDCF of RUSF ingredients (chickpea flour, soy flour, banana, peanut)
• • Relapse from MAM treatment or transfer from SAM treatment
• • Children recently (\<2 months) or enrolled in a nutrition program
• • Residence outside the study area