Comparing SBRT to CRT in Patients With Spinal Metastases

Launched by UNIVERSITY HEALTH NETWORK, TORONTO · Oct 17, 2022

Keywords

ClinConnect Summary

This clinical trial is studying how two different types of radiation therapy—Stereotactic Body Radiation Therapy (SBRT) and Conventional Radiation Therapy (CRT)—affect patients with painful spinal metastases, which are cancers that have spread to the spine from other parts of the body. The goal is to understand how doctors make decisions about which type of treatment to use and to compare the real-world outcomes of these two therapies in patients being treated at the Princess Margaret Cancer Centre.

To participate, individuals must be 18 years or older and have a documented history of cancer with painful spinal metastases that can be treated with radiation. Participants will need to provide written consent and have a performance status that reflects their ability to carry out daily activities. However, those who have previously received radiation in overlapping areas or have certain types of cancers like lymphoma or myeloma are not eligible. If you join this study, you'll help researchers learn more about the effectiveness of these treatments while receiving care tailored to your condition.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Adults 18 years of age or older.
• • Patients seen at the Princess Margaret Cancer Centre with painful spinal metastases amenable to radiation treatment.
• • Confirmation of diagnosis: a) Known/documented prior histological cancer diagnosis
• • Able to provide written consent
• • ECOG performance status 0-3
• Exclusion Criteria:
• • Prior radiotherapy, with fields overlapping, resulting in excessive doses to organs at risk
• • Lymphoma, myeloma or germ cell malignancies