Choroidal Blood Flow in Acute and Chronic Central Serous Chorioretinopathy

Launched by HELSE STAVANGER HF · Oct 18, 2022

Keywords

ClinConnect Summary

This clinical trial is studying a condition called central serous chorioretinopathy (CSC), which affects the eye and can cause vision problems. Researchers want to learn more about how blood flows in the eye by using special imaging techniques. They will look at both acute CSC (which is recent and lasts less than four months) and chronic CSC (which has lasted longer than four months). The goal is to understand the differences in blood flow in these two types of CSC.

To participate in this study, you need to be between 65 and 74 years old and able to give your consent to join. You should have either acute CSC with certain symptoms or chronic CSC that has been affecting your vision for some time. Participants will undergo various non-invasive eye imaging tests, and your eye health will be monitored throughout the study. It’s important to note that people with other serious eye conditions may not be eligible for this trial. If you're interested in learning more or think you might qualify, please reach out for additional information.

Gender

ALL

Eligibility criteria

• • Inclusion Criteria:-
• • Able to sign informed consent
• • Possible to obtain fundus imaging
• * Acute CSC ˂4 months of duration in one eye, defined as:
• • 1. Subfoveal presence of SRF on OCT
• • 2. Present attack is 1st -3rd attack of CSC
• • b) Patient history and examination consistent with acute CSC c) Characteristic appearance of acute CSC on fundus autofluorescence (FAF) and OCT
• * Chronic CSC ≥4 months of duration in one eye, defined as:
• • 1. Subfoveal presence of SRF on OCT
• • 2. Subjective visual loss/symptoms
• • 3. Characteristic appearance of chronic CSC on FAF, fluorescein angiography (FA), and indocyanin angiography (ICGA) and OCT
• • 4. Patient history and examination consistent with chronic CSC
• Exclusion Criteria:
• • History of retinal disease other than CSC (e.g. retinal detachment)
• • Contraindications for FA, ICGA or PDT (only for chronic CSC)