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Search / Trial NCT05591326

The Effect of Using Injectable Platelet-rich Fibrin on Root Surface Closure in Patients with Gingival Recession.

Launched by BERCESTE GULER · Oct 19, 2022

Trial Information

Current as of June 26, 2025

Enrolling by invitation

Keywords

I Prf Creeping Attachment Keratinized Gingival Thickness Gingival Recession

ClinConnect Summary

Gingival recession is the term used to describe the apical positioning of the marginal gingiva from the cemento-enamel junction. Gingival recession can cause hypersensitivity, pain, root caries, cervical erosion and/or abrasion, tooth loss, increased plaque accumulation as a result of exposure of the root surface to the oral environment, and therefore inflammation. Platelet-rich fibrin has been used routinely for more than 20 years to increase keratinized gingival thickness and close gingival recessions due to the growth factors it contains. In a study examining the effect of injectable pla...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Be over 18 years old
  • The patient does not have any systemic disease
  • Presence of at least one tooth with gingival recession in the mandibular or maxillary anterior region
  • Excessive dentin sensitivity and impaired esthetics associated with recession
  • Identifiable enamel-cementum junction in the gingival recession area
  • The tooth is alive and there are no irregularities, grooves, caries and restorations in the area to be treated.
  • No periodontal surgical treatment in the relevant areas in the last 24 months
  • Cases in RT1 class according to 2017 Periodontal Classification according to gingival recession depth
  • Exclusion Criteria:
  • Being outside the specified age range
  • Any contraindication for systematic periodontal surgery
  • Presence of caries, restoration, root concavity in the area to be treated
  • Patients who smoke more than 10 cigarettes per day
  • Patients who use drugs that suppress the immune system or impair healing
  • Patients using drugs that impair bleeding

About Berceste Guler

Berceste Guler is a dedicated clinical trial sponsor committed to advancing medical research and improving patient outcomes through innovative study designs and rigorous scientific methodologies. With a focus on collaboration and integrity, Berceste Guler fosters partnerships with research institutions and healthcare professionals to facilitate the development of cutting-edge therapies. The organization emphasizes ethical considerations and regulatory compliance, ensuring that all trials prioritize participant safety and data integrity. Through its comprehensive approach to clinical trial management, Berceste Guler aims to contribute significantly to the global healthcare landscape.

Locations

Kütahya, , Turkey

Patients applied

0 patients applied

Trial Officials

Berceste Güler

Principal Investigator

Kütahya Health Sciences University Faculty of Dentistry

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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