Neural Bases of Post-stroke Emotion Perception Disorders

Launched by UNIVERSITY HOSPITAL, LILLE · Oct 21, 2022

Keywords

ClinConnect Summary

This clinical trial is looking at how a stroke affects the way people recognize emotions in others. Researchers want to understand the brain processes involved in this by comparing stroke patients to healthy individuals using advanced imaging techniques like MRI and EEG. The goal is to learn more about the emotional challenges that stroke survivors may face.

To participate, stroke patients must be between 18 and 80 years old, have experienced a stroke (either from a blockage or bleeding in the brain) at least six months prior, and be able to give consent. Healthy participants should also be between 18 and 80 but must not have any history of neurological or psychiatric conditions. Participants can expect to undergo some tests that involve brain imaging and answering questions about their emotional health. It's important to know that the study is not yet recruiting, so interested individuals will need to wait until it begins.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• Stroke group:
• • Man or Woman
• • Age 18-80y
• • Unique stroke, ischemic or hemorrhagic
• • at the chronic phase (\< 6 months)
• • Written informed consent
• • subject having a social insurance
• • Subject who consent to complete all the study's experiments
• Healthy controls group:
• • Man or Woman
• • Age 18-80y
• • No history of neurological or psychiatric disease.
• Exclusion Criteria:
• • Stroke group
• • Subject who is unable to consent (due to dementia, severe aphasia, psychiatric disorder...)
• • History of other neurologic disorders
• • Significant le vel of depression or anxiety, assessed by the STAI and the BDI questionnaires
• • Non corrected visual loss
• • Subjects suffering from visual neglect (assessed by the Bells Test and a bisection test (20mm)
• • contra-indications to MRI
• • pregnant or breastfeeding woman
• • Women of childbearing age without effective contraception
• • Healthy controls group
• • Subject who is unable to consent (due to dementia, severe aphasia, psychiatric disorder...)
• • History of neurologic disorders
• • Significant level of depression or anxiety, assessed by the STAI and the BDI questionnaires
• • Non-corrected visual loss
• • contra-indications to MRI
• • pregnant or breastfeeding woman
• • Women of childbearing age without effective contraception