Quadratus Lumborum Block After Cytoreductive Surgery and Hyperthermic Intra-peritoneal Chemotherapy

Launched by GANGNAM SEVERANCE HOSPITAL · Oct 25, 2022

Keywords

ClinConnect Summary

This clinical trial is studying a pain management technique called the quadratus lumborum block (QL block) to see if it can help reduce pain after two specific medical procedures: cytoreductive surgery and hyperthermic intra-peritoneal chemotherapy (CRS and HIPEC). In this trial, participants will be randomly placed in one of two groups: one group will receive the QL block, which involves an injection of a local anesthetic to numb the area, while the other group will not receive this treatment. All patients will also receive standard pain relief medications. The main goal is to find out how much opioid medication participants need in the first 24 hours after surgery, along with how much pain they feel and how quickly they recover.

To join the trial, you must be an adult scheduled for CRS and HIPEC. However, certain individuals won't be eligible, including those with allergies to local anesthetics, chronic pain conditions, or issues that prevent them from using pain control devices. Participants can expect close monitoring of their pain levels and recovery after surgery, and the findings from this study could help improve pain management for future patients undergoing these procedures.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • - Adult patients who are scheduled to undergo cytoreductive surgery and hyperthermic intra-peritoneal chemotherapy (CRS and HIPEC)
• Exclusion Criteria:
• • 1. Allergy to local anesthetics or fentanyl
• • 2. Chronic pain
• • 3. Drug abuse
• • 4. Patients who are unable to use patient-controlled analgesia
• • 5. Skin infection at site for quadratus lomborum block
• • 6. pregnant or breatfeeding women
• • 7. Patients who are unable to communicate