Association Between Dietary Factors and Chronic Subdural Hematoma (DISH)

Launched by BEIJING TIANTAN HOSPITAL · Oct 25, 2022

Keywords

ClinConnect Summary

The DISH trial is researching how different dietary habits and nutrition may be linked to chronic subdural hematoma (CSDH), a condition where blood collects on the surface of the brain. This study involves comparing the diets of patients who have CSDH with those who do not, to see if there are any significant differences. The trial is currently looking for participants who are between 18 and 90 years old, regardless of gender. To be eligible, patients in the CSDH group must have symptoms of the condition confirmed by brain scans, while healthy participants (the control group) should be matched in age and gender but do not have CSDH.

Participants can expect to share information about their diets and nutritional habits. Informed consent will be obtained from the participants or their family members, ensuring everyone understands the study before joining. It's important to note that certain individuals, such as those who have had previous brain surgery for other reasons or who have serious health issues, may not be eligible to participate. This trial aims to shed light on potential dietary factors that could influence the risk of developing CSDH, which may help in prevention and treatment strategies in the future.

Gender

ALL

Eligibility criteria

• • Case group (CSDH group)
• Inclusion Criteria:
• • Patients (18 years to 90 years) presenting with clinical symptoms and neurological deficits of CSDH.
• • CSDH verified on cranial computed tomography or magnetic resonance imaging.
• • Written informed consent from patients or their next of kin according to the patient's cognitive status.
• • Control group (Healthy group)
• Inclusion Criteria:
• • non-CSDH patients (18 years to 90 years) with matched age and gender.
• • Written informed consent from patients or their next of kin according to the patient's cognitive status.
• Exclusion Criteria for both case and control group:
• • Previous intracranial surgery for any neurological disorders but chronic subdural hematoma before.
• • CSDH turned from acute subdural hematoma.
• • Existing malignant tumors, poor medication condition or severe comorbidity.
• • Difficulty in feeding requiring long-term enteral or parenteral nutrition support.
• • Dietary and nutritional survey is estimated to be completed difficultly.
• • Reproductive-age women without verified negative pregnancy testing.
• • Participating in other research.