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Search / Trial NCT05601427

Intra-Operative Adductor Canal Blocks

Launched by OTTAWA HOSPITAL RESEARCH INSTITUTE · Oct 28, 2022

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

ClinConnect Summary

This clinical trial is studying a method called "surgeon-administered adductor canal blocks" (sACB) during total knee arthroplasty (TKA) surgery. The goal is to see if this approach can effectively manage pain after surgery, help patients get moving more quickly, and potentially reduce their hospital stay. Traditionally, these blocks are given by an anesthesiologist before surgery, but this trial will compare that method with the new technique where the surgeon administers the block during the operation.

To participate in this study, you need to be at least 18 years old, scheduled for a primary TKA due to osteoarthritis, and able to provide informed consent. However, there are some reasons you might not be eligible, such as having certain allergies or health conditions, or if you have used specific pain medications recently. If you join the trial, you can expect to be part of a process that could help improve pain management for future knee surgery patients. Your involvement could contribute to valuable insights into the best practices for this type of surgery.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • 1. Male and female patients aged 18 years or older
  • 2. Primary TKA booked as SDD
  • 3. Diagnosis of osteoarthritis
  • Exclusion Criteria:
  • 1. Inability or refusal to sign informed consent form
  • 2. Non-English or French speaking, and no licensed translator, family member or substitute decision maker available.
  • 3. Non-osteoarthritis primary diagnosis
  • 4. Allergy to analgesic medications
  • 5. Contraindication to spinal and/or regional anaesthesia
  • 6. Any use of opioid pain medication within four weeks of the index procedure(13)
  • 7. Pain catastrophizing scale score ≥16 (8, 9, 14)
  • 8. History of cirrhosis
  • 9. History renal insufficiency
  • 10. History or sensory and/or motor neuropathy to the ipsilateral limb
  • 11. Simultaneous, bilateral TKA
  • 12. Non-TKA prosthesis
  • 13. Scheduled for non-SDD TKA.
  • 14. Preoperative varus/valgus of \>10 degrees.
  • 15. Planned General Anaesthetic
  • 16. Use of Intrathecal Morphine

About Ottawa Hospital Research Institute

The Ottawa Hospital Research Institute (OHRI) is a leading academic research institute dedicated to advancing health and healthcare through innovative research and evidence-based practices. Affiliated with The Ottawa Hospital and the University of Ottawa, OHRI fosters a collaborative environment that brings together clinicians, scientists, and trainees to conduct groundbreaking clinical trials and translational research. With a focus on improving patient outcomes, OHRI specializes in a wide range of fields, including cancer, cardiovascular health, and regenerative medicine. The institute is committed to ethical research practices and the dissemination of knowledge to enhance public health and inform healthcare policy.

Locations

Ottawa, Ontario, Canada

Patients applied

0 patients applied

Trial Officials

Simon Garceau, MD

Principal Investigator

The Ottawa Hospital

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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