CBT Augmentation to Promote Medication Discontinuation in Pediatric OCD

Launched by BAYLOR COLLEGE OF MEDICINE · Nov 2, 2022

Keywords

ClinConnect Summary

This clinical trial is looking at how kids and teens with Obsessive-Compulsive Disorder (OCD) can safely stop taking their medication after receiving additional support through Cognitive Behavioral Therapy (CBT). The goal is to see if they can manage their OCD symptoms without going back to using medication over a period of 24 weeks. The study is currently recruiting participants aged 7 to 17 who have been diagnosed with OCD for at least six months and are currently taking stable doses of specific medications for at least 12 weeks.

To be eligible, participants need to have a moderate level of OCD symptoms and both the child and their parent must speak English and live in Texas. It's important to note that children with certain other mental health conditions or who are currently receiving other types of therapy for OCD cannot join the study. If you decide to participate, you can expect to work closely with researchers who will monitor your progress and help you learn how to manage your symptoms effectively.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • The child is between the ages of 7 to 17 at enrollment with a primary diagnosis of OCD of \> 6 months duration based on the Kiddie Schedule for Affective Disorders and Schizophrenia Lifetime Version for DSM-5 (KSADS-PL) and have a CY-BOCS ≥ 16.
• • The child is on stable and maximally tolerated SRI medication (i.e., clomipramine, fluoxetine, fluvoxamine, sertraline, citalopram, escitalopram) for ≥12 weeks given that they are persistently and moderately symptomatic. Paroxetine is exclusionary due to safety concerns.
• • Both the child and parent participating in the study are English speaking.
• • Both the child and their parent participating in the study reside in Texas.
• Exclusion Criteria:
• • The child has a diagnosis of lifetime DSM-5 bipolar disorder, psychotic disorder, and/or intellectual disability.
• • The child has severe current suicidal/homicidal ideation and/or self-injury requiring medical intervention.
• • The child is receiving concurrent psychotherapy for OCD.
• • Initiation of a psychotropic medication less than 4 weeks prior to study enrollment or a stimulant/psychoactive medication less than 2 weeks prior to study enrollment.