Efficacy of Preconditioned Adipose-Derived Stem Cells in Fat Grafting

Launched by UNIVERSITY OF THE PUNJAB · Nov 3, 2022

Keywords

ClinConnect Summary

This clinical trial is studying a new treatment approach to improve facial appearance for patients with conditions like Romberg Disease, Craniofacial Microsomia, burn scars, and post-traumatic scars. Researchers want to find out if using special stem cells, which have been treated with a substance called curcumin, can help make fat grafting (a procedure that adds fat to areas of the face) more effective compared to standard methods. The goal is to see if this treatment can better correct facial deformities and enhance aesthetic outcomes for patients.

To participate in this study, you need to be between 18 and 50 years old, have a body mass index (BMI) between 20 and 30, and be suitable for liposuction based on expected results. You also need to provide your consent to join the trial. However, certain health conditions, like autoimmune diseases, cancer, or severe infections, may prevent you from participating. If you decide to join, you can expect a thorough evaluation and monitoring throughout the study to ensure your safety and the effectiveness of the treatment.

Gender

ALL

Eligibility criteria

• • Inclusion criteria
• • Age 18-50 years (male or female)
• • Body-mass index 20-30 kg/m²
• • Suitable for liposuction as assessed by the expected cosmetic results
• • Provided signed informed consent
• • Exclusion criteria
• • Systemic disorders include autoimmune diseases, hemorrhagic diseases, bone marrow aplasia, sepsis, cancer, and others
• • Local disorders include acne, infections and others
• • Risk factors include smoking, uncompensated diabetes, hypertension, and allergy to the drugs used for general anesthesia
• • Microbiological contamination of either the cell culture or the transplanted tissue