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Search / Trial NCT05611918

REpeated ASSEssment of SurvivorS in Intracerebral Hemorrhage Study

Launched by JOHNS HOPKINS UNIVERSITY · Nov 3, 2022

Trial Information

Current as of June 26, 2025

Enrolling by invitation

Keywords

Intracerebral Hemorrhage Stroke Cognitive Impairment

ClinConnect Summary

The REASSESS study will conduct long-term cognitive, functional, and neuropsychiatric performance assessments to determine if evacuation of spontaneous intracerebral hemorrhage (ICH) reduces the risk of later cognitive decline in the ageing brain. This study will compare rates of cognitive decline under two treatment strategies for intracerebral hemorrhage: the use of minimally invasive surgery with two similar techniques as performed in the MISTIE III and ENRICH trials, and the current standard of care using data from controls in MISTIE III and ENRICH and comparative data from The Ethnic/R...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Participants in the study must be survivors enrolled in MISTIE III and ENRICH trials at end of each trial's final follow-up (day 365 in MISTIE III and day 180 in ENRICH). Relatives of known survivors that are found to be deceased since the end of each trial will be interviewed to capture relevant data.
  • Exclusion Criteria:
  • None

About Johns Hopkins University

Johns Hopkins University, a prestigious research institution located in Baltimore, Maryland, is renowned for its commitment to advancing medical science and public health through innovative clinical trials. With a rich history of groundbreaking research and a multidisciplinary approach, the university's clinical trial initiatives focus on translating scientific discoveries into effective treatments and interventions. Leveraging state-of-the-art facilities and a collaborative network of experts, Johns Hopkins University conducts rigorous clinical studies that aim to improve patient outcomes and address critical health challenges. Its dedication to ethical standards and participant safety underscores its role as a leader in clinical research.

Locations

Ann Arbor, Michigan, United States

Baltimore, Maryland, United States

Stanford, California, United States

San Antonio, Texas, United States

Detroit, Michigan, United States

Albuquerque, New Mexico, United States

Winston Salem, North Carolina, United States

Nashville, Tennessee, United States

Jacksonville, Florida, United States

Philadelphia, Pennsylvania, United States

Louisville, Kentucky, United States

Baltimore, Maryland, United States

Chicago, Illinois, United States

New Haven, Connecticut, United States

La Jolla, California, United States

Cincinnati, Ohio, United States

Fairway, Kansas, United States

Birmingham, Alabama, United States

Minneapolis, Minnesota, United States

Ann Arbor, Michigan, United States

Sacramento, California, United States

Chicago, Illinois, United States

Saint Louis, Missouri, United States

Piscataway, New Jersey, United States

Bronx, New York, United States

Houston, Texas, United States

Fairfax, Virginia, United States

Patients applied

0 patients applied

Trial Officials

Wendy Ziai, MD

Principal Investigator

Johns Hopkins University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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