Acoustic Analysis of VA Sounds

Launched by MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH · Nov 3, 2022

Keywords

ClinConnect Summary

This clinical trial is investigating a new way to monitor vascular access (VA) sounds in patients with end-stage renal disease (ESRD) who need hemodialysis (HD). The study aims to see if recording and analyzing the sounds from the VA—where blood is accessed for dialysis—can help doctors detect problems before they become serious. Currently, many patients experience issues with their vascular access, leading to the need for new surgeries. By identifying patients at risk of access failure, healthcare providers can intervene early and potentially prevent complications.

To participate in this study, patients must be between the ages of 65 and 87 and need a new vascular access for hemodialysis. They should be able to give informed consent and have not had any major contraindications that would prevent the creation of a vascular access. Participants will undergo sound recording and ultrasound examinations of their vascular access while receiving treatment. This study is a single center observational study, meaning it will take place at one location and will focus on collecting information to help improve future care for patients needing vascular access for dialysis.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Provision of informed consent prior to any study specific procedures.
• • 2. Patients in HD treatment that need a new VA or patients that entered the pre-dialysis program because of ESRD. In all these cases the treatment of first choice should be the creation of a distal autogenous AVF, the creation of an AVG or the proximalization of an occluded VA.
• Exclusion Criteria:
• • 1. Contraindications for the creation of an autogenous AVF, for the AVG creation or the proximalization of a failed VA.
• • 2. Patients who use catheter to perform HD.
• • 3. Patients undergoing peritoneal dialysis.
• • 4. Patients with life expectancy less than 2 years.