Laser Versus Cryotherapy for the Treatment of Recalcitrant Warts

Launched by THE 306 HOSPITAL OF PEOPLE'S LIBERATION ARMY · Nov 7, 2022

Keywords

ClinConnect Summary

This clinical trial is studying two different treatments for stubborn warts that haven't responded well to other therapies. It aims to find out if laser treatment is more effective than cryotherapy, which involves freezing the warts. The trial is looking for adults aged 18 and older who have specific types of warts caused by certain viruses and have had these warts for over a year. Participants should have no more than ten warts and should not have had more than two cryotherapy treatments in the past.

If you decide to participate, you will receive either laser treatment or cryotherapy, and the effectiveness of each method will be compared. However, there are some important factors to consider before joining, such as not currently being part of another clinical trial, not having certain medical conditions (like autoimmune diseases or pregnancy), and not using specific medications that could affect healing. The trial is not yet recruiting participants, but it aims to help improve treatment options for those who struggle with recalcitrant warts.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients with HPV2/27/57-induced recalcitrant warts, including periungualor mosaic warts, common or plantar warts with a duration of longer than 1 year, and common or plantar warts previously received no more than two sessions of cryotherapy
• • Total number of warts is ≤10 .
• • Aged 18 years or older.
• Exclusion Criteria:
• • Patients are currently participating in another trial for the treatment of cutaneous warts.
• • Patients have taken immunosuppressant drugs (such as oral corticosteroids) during the past three months.
• • Patients have impaired healing eg due to diabetes, vitamin A deficiency, hyperthyroidism and hypothyroidism.
• • Patients have autoimmune diseases (such as systemic lupus erythematosus, dermatomyositis, scleroderma or other diseases).
• • Patients are pregnant or ready for pregnancies or breast-feeding.
• • Patients have cold intolerance (such as cold urticaria, cryoglobulinaemia, cold agglutinin syndrome or Raynaud's syndrome).
• • Patients have local pain intolerance.
• • Patients have local hypoesthesia.
• • Patients are unable to tolerate laser or cryotherapy.