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Search / Trial NCT05620784

Intra-operative Loop Diuretics to Improve Same-day Discharge Rates After HoLEP

Launched by NORTHWESTERN UNIVERSITY · Nov 11, 2022

Trial Information

Current as of June 27, 2025

Recruiting

Keywords

ClinConnect Summary

This clinical trial is studying whether the use of a medication called furosemide, given during a specific type of prostate surgery known as Holmium Laser Enucleation of the Prostate (HoLEP), can help more patients go home on the same day of their surgery. HoLEP is a treatment for benign prostatic hyperplasia (BPH), a condition that can cause urinary problems. The trial aims to see if giving furosemide, which helps the body produce urine, makes a difference in how quickly patients can be discharged after the procedure.

To be eligible for this study, participants must be men aged 18 to 89 who are planning to undergo HoLEP and can provide informed consent. However, those with known allergies to furosemide, certain severe medical conditions, or those needing other surgeries at the same time will not be included. Participants in the trial can expect to have regular assessments and questionnaires about their experience, and their results will help determine the best practices for future patients undergoing HoLEP.

Gender

MALE

Eligibility criteria

  • Inclusion Criteria:
  • Males 18 -89 undergoing HoLEP
  • Willing to sign the Informed Consent Form
  • Able to read, understand, and complete patient questionnaires.
  • Exclusion Criteria:
  • Allergy or hypersensitivity to furosemide or other loop diuretic
  • Anuric patients or patients with liver failure
  • Patients having a concurrent ureteroscopy +/- laser lithotripsy, percutaneous nephrolithotomy, or non-urologic surgery at the time of their HoLEP
  • Anticipated need for perineal urethrostomy at the time of HoLEP
  • Patient not undergoing catheter removal and voiding trial at Northwestern Memorial Hospital

About Northwestern University

Northwestern University is a prestigious academic institution renowned for its commitment to advancing medical research and improving patient care through innovative clinical trials. With a robust infrastructure that supports interdisciplinary collaboration, Northwestern leverages its expertise in various fields, including medicine, engineering, and social sciences, to drive groundbreaking studies. The university is dedicated to adhering to the highest ethical standards and regulatory compliance, ensuring that all clinical trials are conducted with the utmost integrity and focus on participant safety. Through its Clinical Trials Office, Northwestern aims to translate scientific discoveries into effective therapies, ultimately enhancing health outcomes and contributing to the broader medical community.

Locations

Chicago, Illinois, United States

Patients applied

0 patients applied

Trial Officials

Amy E Krambeck, MD

Principal Investigator

Northwestern Medicine

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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