Transpulmonary Pressure in Right Ventricle Protection of ARDS

Launched by BEIJING CHAO YANG HOSPITAL · Nov 18, 2022

Keywords

ClinConnect Summary

This clinical trial is looking at different ways to help patients with Acute Respiratory Distress Syndrome (ARDS), a serious condition that affects breathing. Specifically, the study is comparing two types of mechanical ventilation strategies: one that is based on a measurement called transpulmonary pressure, and another that follows a traditional approach known as lung protective ventilation. The goal is to see which method better protects the right side of the heart while treating ARDS.

To participate in this trial, individuals need to be at least 18 years old and have been on mechanical ventilation for less than 72 hours, while also meeting specific criteria for ARDS. However, some people may not be eligible if they have had certain types of surgeries, severe lung issues, or other serious health conditions. For those who join, they can expect close monitoring and care as they receive one of the two ventilation strategies being tested. This trial is currently recruiting participants, and it aims to improve treatment for patients facing this challenging condition.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • duration of invasive mechanical ventilation less than 72 hours;
• • meet the diagnostic criteria of Berlin definition for ARDS;
• • age older than 18
• Exclusion Criteria:
• • esophageal surgery or damage;
• • cardiac surgery;
• • severe bronchopleural fistula;
• • serious arrhythmia; pneumothorax;
• • tricuspid stenosis;
• • heparin allergy;
• • chronic pulmonary heart disease