Breathing & Blood Pressure

Launched by FLORIDA STATE UNIVERSITY · Nov 18, 2022

Keywords

ClinConnect Summary

The "Breathing & Blood Pressure" clinical trial is researching how obesity affects the heart and blood pressure responses during different breathing exercises. The goal is to better understand these effects in people who are healthy but overweight or obese. If you are between the ages of 18 and 65 and have a body mass index (BMI) of 40 or less, you might be eligible to participate. However, there are some important health conditions that would exclude you from joining, such as uncontrolled high blood pressure or certain heart and lung issues.

If you choose to participate, you can expect to take part in various breathing activities to help researchers measure how your heart and blood pressure respond. The study is currently looking for volunteers, and it's a chance to contribute to important research that could improve understanding of cardiovascular health in individuals with obesity. Keep in mind that this trial is not for individuals with significant health problems, recent surgeries, or those under 18 years old.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • • Body mass index values of ≤40 kg/m\^2
• Exclusion Criteria:
• • Not weight stable (\<5% change in body mass over the past six months)
• • Overt cardiovascular, neurological, renal, liver, and/or metabolic illness (e.g., diabetes mellitus)
• • Current, or history of uncontrolled, Stage 2 hypertension (blood pressure \>140 / 90 mmHg; anti-hypertensive medications are permitted)
• • Diagnosed obstructive sleep apnea
• • Previous bariatric surgery
• • Diagnosis or signs (e.g., values below the lower limit of normal) of overt airway disease(s)
• • Current or recent (regular use within the past 6 months) use of tobacco or nicotine products (e.g., cigarettes, vaping)
• * Per the POWERbreathe® company:
• • Patients who have undergone recent abdominal surgery and those with abdominal hernia.
• • Asthma patients who have a very low symptom perception and suffer from frequent, severe exacerbations or with an abnormally low perception of dyspnoea.
• • If a patient is suffering from a ruptured eardrum or any other condition of the ear.
• • Patients with marked elevated left ventricular end-diastolic volume and pressure.
• • Patients with worsening heart failure signs and symptoms after a respiratory/inspiratory muscle training (IMT) session
• • If you are suffering from a cold, sinusitis, or respiratory tract infection, we advise that you do not use your POWERbreathe IMT device.
• • Individuals who are not yet adults (infants, children, teenagers)
• • Pregnant (self-reported and urine pregnancy test conducted), lactating (self-reported), or post-menopausal (self-reported) females
• • Prisoners