Change in MAPSE During Treatment of Sepsis
Launched by UNIVERSITY OF MARYLAND, BALTIMORE · Nov 22, 2022
Trial Information
Current as of June 26, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying how a specific heart measurement changes in patients with sepsis, a serious condition caused by infections in the bloodstream. Researchers want to see if treatment for septic shock improves the heart's ability to pump blood by looking at a measurement called MAPSE, which shows how well the heart's mitral valve is moving. To do this, they will use an ultrasound, a safe and painless imaging technique, to take pictures of the heart and measure MAPSE before and after treatment.
To participate in this study, patients must be diagnosed with sepsis or septic shock and be between the ages of 18 and 74. Unfortunately, those who are under 18, currently in the emergency department, or unable to give consent are not eligible. Participants can expect to have an ultrasound done to measure their heart function at the beginning of the study and again after they receive treatment for their infection. This trial aims to help improve our understanding of how sepsis affects the heart and how treatment can help patients recover.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Diagnosis of Sepsis or Septic Shock
- Exclusion Criteria:
- • Age equal to or less than 17
- • patient in the emergency department
- • Unable to perform POCUS exam due to medical necessity
- • Patients without sepsis
- • unable to obtain consent or have a legal representative consent
About University Of Maryland, Baltimore
The University of Maryland, Baltimore (UMB) is a leading academic institution dedicated to advancing healthcare through innovative research and clinical trials. As a prominent sponsor of clinical studies, UMB leverages its extensive resources and expertise across various disciplines, including medicine, pharmacy, nursing, and social work, to contribute to groundbreaking discoveries and improve patient outcomes. Committed to ethical research practices and collaboration, UMB fosters an environment that promotes the translation of scientific knowledge into real-world applications, ultimately enhancing the well-being of diverse populations.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Baltimore, Maryland, United States
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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