Construction of a Database for TMA

Launched by THE FIRST AFFILIATED HOSPITAL OF SOOCHOW UNIVERSITY · Nov 22, 2022

Keywords

ClinConnect Summary

This clinical trial is focused on studying a condition called Thrombotic Microangiopathies (TMA), which involves problems with blood clotting that can affect various organs in the body. Researchers are gathering information about patients by reviewing medical records and following up with them over the phone or during outpatient visits. The goal is to build a comprehensive database of at least 200 cases at the First Affiliated Hospital of Soochow University from December 2022 to November 2027. They will collect details like patients' ages, genders, and specific clinical information related to TMA.

To be eligible for this study, patients should have certain laboratory test results, such as high levels of a substance called lactate dehydrogenase, low platelet counts, or specific blood cell abnormalities. It’s important that participants are willing to cooperate with the study procedures. If you or someone you know is affected by this condition and meets the criteria, participating in this trial could help researchers learn more about TMA and potentially improve future treatments.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • The patient has elevated lactate dehydrogenase to more than twice the baseline value, platelets less than 20 or decreased by more than 50% within 24 hours, and more than 2% of schistocytes visible on a peripheral blood smear. Alternatively, pathological sections show extensive micro thrombosis.
• Exclusion Criteria:
• • The investigator considers the subject unable or unwilling to cooperate with the study procedures.