Neutrophil-to-lymphocyte and Platelet-to-lymphocyte Ratio in Predicting the Incidence of Nausea and Vomiting
Launched by QIANFOSHAN HOSPITAL · Dec 2, 2022
Trial Information
Current as of February 05, 2025
Unknown status
Keywords
ClinConnect Summary
Hemophilia arthropathy is a debilitating complication of hemophilia that occurs primarily in severe forms with recurrent spontaneous intra-articular hemorrhage, with the knee being the most commonly affected joint. Currently, total knee arthroplasty is the standard treatment for end-stage hemophilic arthropathy. Due to the special disease of hemophilia, general anesthesia is often chosen as the preferred anesthesia method, and the risk of bleeding is lower than that of neuraxial anesthesia. However, 20 to 30 percent of surgical patients suffer from post-operative nausea and vomiting after g...
Gender
MALE
Eligibility criteria
- Inclusion Criteria:
- • 1. The patients with hemophilia A undergoing unilateral total knee arthroplasty.
- • 2. The age of the patients ranged from 18 to 70 years.
- • 3. American Society of Anesthesiologists is graded as I\~III
- • 4. No history of mental illness
- • 5. No history of antiemetic and anticholinergic drugs.
- • 6. No history of serious gastrointestinal diseases.
- Exclusion Criteria:
- • 1. Patients who have received long-term steroid treatment
- • 2. Patients who need more than 2.5 mg neostigmine to reverse muscle relaxants
- • 3. Patients with previous malignant tumor, malabsorption, morbid obesity, hypogonadism, thyroid and parathyroid diseases and autoimmune diseases.
Trial Officials
Yuelan Wang
Principal Investigator
China, Shandong Qianfoshan Hospital
About Qianfoshan Hospital
Qianfoshan Hospital is a leading medical institution dedicated to advancing healthcare through innovative clinical research and trials. Located in Shandong Province, China, the hospital is renowned for its commitment to excellence in patient care and medical education. With a multidisciplinary team of experienced professionals, Qianfoshan Hospital focuses on a wide range of therapeutic areas, striving to enhance treatment options and improve patient outcomes. The institution actively collaborates with various stakeholders to ensure the highest standards of ethics and efficacy in its clinical research endeavors.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Jinan, Shandong, China
People applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
Discussion 0
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