Trials
Search / Trial NCT05636163

Neutrophil-to-lymphocyte and Platelet-to-lymphocyte Ratio in Predicting the Incidence of Nausea and Vomiting

Launched by QIANFOSHAN HOSPITAL · Dec 2, 2022

Trial Information

Current as of January 22, 2025

Unknown status

Keywords

Neutrophil Lymphocyte Platelet Hemophilia Post Operative Nausea And Vomiting

ClinConnect Summary

Hemophilia arthropathy is a debilitating complication of hemophilia that occurs primarily in severe forms with recurrent spontaneous intra-articular hemorrhage, with the knee being the most commonly affected joint. Currently, total knee arthroplasty is the standard treatment for end-stage hemophilic arthropathy. Due to the special disease of hemophilia, general anesthesia is often chosen as the preferred anesthesia method, and the risk of bleeding is lower than that of neuraxial anesthesia. However, 20 to 30 percent of surgical patients suffer from post-operative nausea and vomiting after g...

Gender

MALE

Eligibility criteria

  • Inclusion Criteria:
  • 1. The patients with hemophilia A undergoing unilateral total knee arthroplasty.
  • 2. The age of the patients ranged from 18 to 70 years.
  • 3. American Society of Anesthesiologists is graded as I\~III
  • 4. No history of mental illness
  • 5. No history of antiemetic and anticholinergic drugs.
  • 6. No history of serious gastrointestinal diseases.
  • Exclusion Criteria:
  • 1. Patients who have received long-term steroid treatment
  • 2. Patients who need more than 2.5 mg neostigmine to reverse muscle relaxants
  • 3. Patients with previous malignant tumor, malabsorption, morbid obesity, hypogonadism, thyroid and parathyroid diseases and autoimmune diseases.

Trial Officials

Yuelan Wang

Principal Investigator

China, Shandong Qianfoshan Hospital

About Qianfoshan Hospital

Qianfoshan Hospital is a leading medical institution dedicated to advancing healthcare through innovative clinical research and trials. Located in Shandong Province, China, the hospital is renowned for its commitment to excellence in patient care and medical education. With a multidisciplinary team of experienced professionals, Qianfoshan Hospital focuses on a wide range of therapeutic areas, striving to enhance treatment options and improve patient outcomes. The institution actively collaborates with various stakeholders to ensure the highest standards of ethics and efficacy in its clinical research endeavors.

Locations

Jinan, Shandong, China

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0

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