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Search / Trial NCT05636202

The Role of NLR in the Diagnosis and Prognosis of Sepsis

Launched by WUHAN UNION HOSPITAL, CHINA · Nov 22, 2022

Trial Information

Current as of February 05, 2025

Completed

Keywords

Sepsis Nlr Percentage Of Neutrophils Prognosis

ClinConnect Summary

Sepsis is defined as a life-threatening organ dysfunction caused by the host's malfunctioning response to infection, which has become one of the major problems in the world's public health. The development of effective biomarkers for the diagnosis of sepsis is undoubtedly helpful for us to timely and accurately understand the diagnosis, progression, and prognosis of sepsis.

The neutrophil-to-lymphocyte ratio (NLR), as an inflammatory indicator, is inexpensive and easily accessible parameter and could be widely used. In severe infectious diseases, particularly in sepsis, a substantial incre...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • 1.Patients with sepsis
  • 2.ICU stay time ≥3 days;
  • Exclusion Criteria:
  • 1. History of solid organ or bone marrow transplantation;
  • 2. Diseases that may affect immune-related indicators, such as autoimmune diseases such as rheumatoid arthritis and SLE, or hematological malignancies such as leukemia and lymphoma;
  • 3. Have received radiotherapy or chemotherapy within the past 30 days, or have received immunosuppressive drugs (tripterygium, mycophenolate, cyclophosphamide, FK506, etc.), or have received continuous treatment with more than 10mg of prednisolone/day (or the same dose of other hormones);
  • 4. Pregnancy or lactation;c

About Wuhan Union Hospital, China

Wuhan Union Hospital, affiliated with Huazhong University of Science and Technology, is a leading medical institution located in Wuhan, China. Renowned for its comprehensive healthcare services and advanced research capabilities, the hospital plays a pivotal role in clinical trials aimed at enhancing medical knowledge and patient care. With a commitment to innovation and excellence, Wuhan Union Hospital collaborates with various stakeholders to conduct rigorous and ethically sound clinical research, contributing significantly to the advancement of medical science and public health both domestically and internationally.

Locations

Wuhan, Hubei, China

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0

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