Determination of the ED50 and ED95 of Prophylactic Norepinephrine Infusion for Preventing Post-induction Hypotension in Elderly Patients Undergoing Major Abdominal Surgery
Launched by SECOND AFFILIATED HOSPITAL, SCHOOL OF MEDICINE, ZHEJIANG UNIVERSITY · Nov 28, 2022
Trial Information
Current as of July 05, 2025
Unknown status
Keywords
ClinConnect Summary
No description provided
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • aged 65 to 80 years
- • Undergoing major abdominal surgery
- • American Society of Anesthesiologists (ASA) physical status of I/II/III
- Exclusion Criteria:
- • Patient refusal
- • Severe untreated or uncontrolled hypertension despite medications
- • Bradycardia (heart rate \< 50 beat per minute)
- • Cardiac morbidities, heart block greater than the first degree
- • Severe hepatic and renal dysfunction
- • hyperthyroidism
- • vascular diseases
- • BMI\>30
- • Monoamine oxidase inhibitors were used 2 weeks before surgery
About Second Affiliated Hospital, School Of Medicine, Zhejiang University
The Second Affiliated Hospital of Zhejiang University School of Medicine is a leading clinical research institution dedicated to advancing healthcare through innovative medical practices and rigorous scientific inquiry. With a robust infrastructure and a multidisciplinary team of experienced researchers and clinicians, the hospital is committed to conducting high-quality clinical trials that address critical health challenges. As an integral part of Zhejiang University, the hospital leverages academic expertise and cutting-edge technology to foster collaboration in research, education, and patient care, ultimately aiming to improve patient outcomes and contribute to the global medical community.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Hangzhou, Zhejiang, China
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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