Multisite Transcranial Direct Current Stimulation to Promote Hand Function Recovery After Stroke

Launched by CHINESE UNIVERSITY OF HONG KONG · Nov 27, 2022

Keywords

ClinConnect Summary

This clinical trial is exploring a new treatment called multisite high definition transcranial direct current stimulation (HD-tDCS) to help improve hand function in people who have had a stroke. The goal is to see if this advanced stimulation technique can enhance the brain's ability to control movement more effectively than traditional methods. By using special computer modeling, researchers can customize where the electrodes are placed based on each person's unique brain and stroke characteristics, aiming to boost recovery in a more targeted way.

To join the study, participants should be at least 65 years old and have had their first stroke more than 12 months ago, with mild to moderate difficulties in using their hands. They should still have some ability to move their fingers and understand instructions. However, individuals with a history of seizures or certain other medical conditions may not be eligible. Participants can expect to receive personalized care and may have the chance to improve their hand function through this innovative approach.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • first-ever stroke, the duration after stroke exceeds 12 months;
• • mild to moderate upper extremity motor function deficit, determined by the Fugl-meyer assessment of upper extremity (FMAUE) scores between 15 and 53;
• • detectable voluntary muscle sEMG signal from flexor digitorum (FD) and extensor digitorum (ED);
• • scored below 3 in the Modified Ashworh Score (MAS) of FD and ED;
• • sufficient cognitive function to follow the assessment and training instructions, determined by Mini Mental State Examination score of more than 21.
• Exclusion Criteria:
• • history of epilepsy, or any other contradictions of brain stimulation;
• • severe joint contracture of elbow or shoulder, or pain induced by any other neurological, neuromuscular, and orthopedic diseases.