EFFECT OF SCALING ON SERUM hsCRP LEVELS AND PERIODONTAL PARAMETERS IN SYSTEMICALLY HEALTHY YOUNG WOMEN WITH GINGIVITIS

Launched by POSTGRADUATE INSTITUTE OF DENTAL SCIENCES ROHTAK · Nov 26, 2022

Keywords

ClinConnect Summary

Gingivitis is a highly prevalent chronic bacterial disease in susceptible children, adults and the elderly, persisting for decades in subjects, and is an essential precursor of periodontitis. Several studies have shown periodontitis and subgingival P. gingivalis to be associated with increased C-reactive protein (CRP) levels and CRP has been implicated as a possible mediator of the association between periodontitis and several systemic diseases Limited data are available today addressing detrimental systemic effects of experimental or natural gingivitis as they have been rarely investigated...

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • females of reproductive age group (18-40 yrs)
• • BMI (18.5 - 24.9)
• • presence of ≥20 natural teeth
• • Healthy periodontium (for control group) defined as bleeding on probing at \< 10% of sites, with pockets ≤3 mm, no probing attachment loss and no radiologic bone loss.
• • Gingivitis (17) (for test group) Gingivitis (intact periodontium) is defined as bleeding on probing at ≥ 10% of sites, with pockets ≤3 mm, no probing attachment loss and no radiologic bone loss.
• • Gingivitis (reduced periodontium) is defined as bleeding on probing at ≥ 10% of sites with pockets ≤3 mm with possible probing attachment loss and possible radiologic bone loss.
• • Localized gingivitis is defined as 10-30% of bleeding sites. Generalized gingivitis is defined as more than 30% of bleeding sites.
• Exclusion Criteria:
• • history of androgen-secreting tumors, congenital adrenal hyperplasia and thyroid dysfunction
• • nephrotic syndrome, chronic renal failure, significant cardiovascular disease, established type 1 or type 2 diabetes mellitus, active cancer within the last past 5 years
• • smokers and alcoholics
• • history of systemic antibiotics or oral contraceptives usage within last 3 months
• • periapical pathology or oral inflammatory conditions other than gingivitis.
• • any periodontal treatment within 6 months prior to study Patients with pockets ≥ 3 mm and probing attachment loss shall be excluded, hence, radiographic examination will not be needed.