Vaginal Microbiome and HPV Pre-malignant and Cervical Dysplasia

Launched by HADASSAH MEDICAL ORGANIZATION · Nov 28, 2022

Keywords

ClinConnect Summary

This clinical trial is studying the relationship between the vaginal microbiome (the collection of bacteria and other microorganisms in the vagina) and the presence of Human Papilloma Virus (HPV) in women with certain cervical health issues, such as pre-cancerous changes and cervical dysplasia. The goal is to gather detailed information about how the vaginal microbiome may influence the development of cervical conditions, helping researchers understand if it can play a role in the progression from healthy to unhealthy cervical cells.

To be eligible for this study, women aged 25 to 70 who have recently visited a clinic for a Pap smear or colposcopy may participate. However, participants cannot have used antibiotics in the month before their visit, taken any vaginal medications or treatments in the week before sample collection, be currently menstruating, or be pregnant. If you join the study, you will provide samples that will be analyzed to help create a larger dataset comparing women with and without cervical issues. This research could contribute to better understanding and management of cervical health in the future.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Age 25-70
• • Attended the clinic for a Pap smear or colposcopy
• Exclusion Criteria:
• • Patient does not approve sample collection
• • Usage of antibiotics in the month prior to clinic visit
• • Usage of any vaginal preparation or medication in the week prior to sample collection (anti-fungal, spermicides, lubricant etc.)
• • Menstruation
• • Pregnancy