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Search / Trial NCT05641233

Preoperative Radiotherapy in Patients at High Risk of Postoperative Pancreatic Fistula After Pancreatoduodenectomy

Launched by ERASMUS MEDICAL CENTER · Nov 29, 2022

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Trial Information

Current as of February 05, 2025

Unknown status

Keywords

Post Operative Pancreatic Fistula Stereotactic Radiotherapy Pancreatic Fibrosis Pancreatoduodenectomy

ClinConnect Summary

No description provided

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • • Patients scheduled to undergo pancreatoduodenectomy for another indication than pancreatic ductal adenocarcinoma.
  • • Pancreatic duct diameter ≤ 3 millimetres, measured on the diagnostic CT scan (at the level of the portomesenteric vein, at the pancreatic neck, the future anastomotic site).
  • • WHO-ECOG performance status 0,1 or 2.
  • • Ability to undergo stereotactic radiotherapy and surgery.
  • • Age ≥ 18 years.
  • • Good understanding of the oral and written patient information provided.
  • • Written informed consent.
  • Exclusion Criteria:
  • • Patients undergoing pancreatoduodenectomy for (suspected) pancreatic cancer, chronic pancreatitis, or benign neoplasms (e.g. serous cyst) in the periampullary region.
  • • Patients with (a history of) chronic pancreatitis

About Erasmus Medical Center

Erasmus Medical Center, located in Rotterdam, Netherlands, is a leading academic medical center renowned for its commitment to advancing healthcare through innovative research and clinical trials. As a prominent institution within the Erasmus University Rotterdam, the center integrates cutting-edge scientific inquiry with comprehensive patient care, focusing on a wide range of medical specialties. With a strong emphasis on multidisciplinary collaboration, Erasmus Medical Center aims to translate research findings into tangible clinical applications, enhancing treatment options and improving patient outcomes. The institution is dedicated to conducting ethical and rigorous clinical trials that contribute to the global body of medical knowledge and foster advancements in personalized medicine.

Locations

Amsterdam, North Holland, Netherlands

Rotterdam, South Holland, Netherlands

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0

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