Nebulized Versus Intravenous Dexmedetomidine for Sevoflurane Induced Emergence Agitation After Pediatric Tonsillectomy

Launched by ASSIUT UNIVERSITY · Nov 29, 2022

Keywords

ClinConnect Summary

This clinical trial is looking at two different ways to prevent a condition called emergence agitation (EA) in children after they have surgery to remove their tonsils, which is a common procedure. Emergence agitation can cause children to become very restless or confused as they wake up from anesthesia, which can lead to breathing problems. The researchers want to compare the effectiveness of giving a medication called dexmedetomidine either through a nebulizer (a device that turns liquid medicine into mist for inhalation) or through an intravenous (IV) line, to see which method works better in keeping children calm after their surgery.

To participate in this study, children must be between 3 to 7 years old and scheduled for a tonsil surgery, with or without other procedures like adenoid removal or ear tube placement. However, certain children won't be able to join, such as those with behavioral issues, certain medical conditions, or those taking specific medications. If enrolled, participants will receive one of the two treatments before their surgery and will be monitored for any signs of agitation as they wake up. This study aims to improve recovery experiences for young patients and their families after tonsillectomy surgeries.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • ASA I and II
• • Children scheduled for tonsillectomy with or without adenoidectomy with or without myringotomy, and/or tympanostomy tube insertion.
• Exclusion Criteria:
• • Patient's guardian refusal to participate in the study.
• • Children with Behavioral changes; physical or developmental delay; neurological disorder or psychological disorder.
• • Children on sedative or anticonvulsant medication.
• • history of sleep apnea
• • significant organ dysfunction, cardiac dysrhythmia, congenital heart disease
• • Known allergy to the study drugs.