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Search / Trial NCT05641571

Effects of an Exercise Intervention on Taxane-induced Peripheral Neuropathy in Breast Cancer Survivors

Launched by TAICHUNG VETERANS GENERAL HOSPITAL · Nov 30, 2022

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Trial Information

Current as of February 05, 2025

Unknown status

Keywords

Taxane Induced Peripheral Neuropathy, Extremity Exercise

ClinConnect Summary

The incidence of breast cancer increases yearly. Taxane is one of the main chemotherapy drugs for breast cancer treatment. Taxane-induced peripheral neuropathy (TIPN) impairs breast cancer survivors' functioning, increases the risk of falls, and impacts quality of life (QOL). As TIPN worsens, there is a need to decrease chemotherapy dosage or terminate treatment. This may reduce the effect of chemotherapy, in addition, to increasing survivor's mortality. Up to date, no evidence-based, effective nonpharmacologic intervention to prevent or manage TIPN. Furthermore, no interventions were recom...

Gender

FEMALE

Eligibility criteria

  • Inclusion Criteria:
  • • Participants will be randomly allocated to the experimental or observational group using the two strata: (1) adjuvant or neoadjuvant and (2) paclitaxel, docetaxel, or Taxane plus Platinum.
  • Exclusion Criteria:
  • • Participants who have peripheral neuropathy before chemotherapy or regular exercise are excluded.

Trial Officials

Chih-Chiang Hung, Doctor

Principal Investigator

Taichung Veterans General Hospital

About Taichung Veterans General Hospital

Taichung Veterans General Hospital is a leading medical institution in Taiwan, renowned for its commitment to advancing healthcare through innovative research and clinical trials. As a prominent sponsor of clinical studies, the hospital leverages its extensive expertise in various medical fields to facilitate the development of new therapies and improve patient outcomes. With a focus on patient-centered care and adherence to rigorous ethical standards, Taichung Veterans General Hospital plays a pivotal role in bridging the gap between research and clinical practice, fostering collaborations that contribute to the global medical community.

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Timeline

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Trial launched

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Estimated completion

Not reported

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