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Is Monocyte/HDL Ratio a Predictor of Mortality in Aortic Valve Surgery

Launched by BAKIRKOY DR. SADI KONUK RESEARCH AND TRAINING HOSPITAL · Dec 6, 2022

Trial Information

Current as of January 16, 2025

Completed

Keywords

ClinConnect Summary

Inflammation is causally associated with both coronary artery disease and aortic stenosis. Although aortic stenosis is considered a static degenerative and calcific process, recent evidence has shown the opposite. The role of inflammation in the pathogenesis of AS It will be investigated that mortality may be associated with increased inflammation in patients treated with AVR.

Adult patients (aged ≥18 years) with ASA II-IV who underwent elective aortic valve replacement under cardiopulmonary bypass (CPB) due to aortic stenosis in our clinic between January 1, 2010 and March 31, 2022, will ...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • be over the age of 18, ASA II-IV Patients scheduled for cardiac surgery due to on-pomp aortic valve replacement
  • Exclusion Criteria:
  • emergency operations, off pump)pumpless surgery, revision (repetitive) operations, those with signs of acute infection, those with autoimmune disease, those with severe renal (serum creatinine \>2.0 mg/dl) disease, those with severe hepatic disease, those with suspected malignancy, patients where data variables cannot be saved due to technical problems.

Trial Officials

tuğba yücel, md

Principal Investigator

Bakirkoy Dr Sadi Konuk Traning Hospital

About Bakirkoy Dr. Sadi Konuk Research And Training Hospital

Bakirkoy Dr. Sadi Konuk Research and Training Hospital is a leading healthcare institution dedicated to advancing medical research and education. Located in Istanbul, Turkey, the hospital combines clinical excellence with a robust research framework, focusing on innovative treatment methodologies and patient care. As a prominent clinical trial sponsor, it fosters collaboration among multidisciplinary teams to facilitate groundbreaking studies that enhance medical knowledge and improve health outcomes. The institution is committed to adhering to the highest ethical standards and regulatory guidelines, ensuring the integrity and reliability of its research initiatives.

Locations

Istanbul, Bakırköy, Turkey

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0

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