Is Monocyte/HDL Ratio a Predictor of Mortality in Aortic Valve Surgery
Launched by BAKIRKOY DR. SADI KONUK RESEARCH AND TRAINING HOSPITAL · Dec 6, 2022
Trial Information
Current as of February 05, 2025
Completed
Keywords
ClinConnect Summary
Inflammation is causally associated with both coronary artery disease and aortic stenosis. Although aortic stenosis is considered a static degenerative and calcific process, recent evidence has shown the opposite. The role of inflammation in the pathogenesis of AS It will be investigated that mortality may be associated with increased inflammation in patients treated with AVR.
Adult patients (aged ≥18 years) with ASA II-IV who underwent elective aortic valve replacement under cardiopulmonary bypass (CPB) due to aortic stenosis in our clinic between January 1, 2010 and March 31, 2022, will ...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • be over the age of 18, ASA II-IV Patients scheduled for cardiac surgery due to on-pomp aortic valve replacement
- Exclusion Criteria:
- • emergency operations, off pump)pumpless surgery, revision (repetitive) operations, those with signs of acute infection, those with autoimmune disease, those with severe renal (serum creatinine \>2.0 mg/dl) disease, those with severe hepatic disease, those with suspected malignancy, patients where data variables cannot be saved due to technical problems.
Trial Officials
tuğba yücel, md
Principal Investigator
Bakirkoy Dr Sadi Konuk Traning Hospital
About Bakirkoy Dr. Sadi Konuk Research And Training Hospital
Bakirkoy Dr. Sadi Konuk Research and Training Hospital is a leading healthcare institution dedicated to advancing medical research and education. Located in Istanbul, Turkey, the hospital combines clinical excellence with a robust research framework, focusing on innovative treatment methodologies and patient care. As a prominent clinical trial sponsor, it fosters collaboration among multidisciplinary teams to facilitate groundbreaking studies that enhance medical knowledge and improve health outcomes. The institution is committed to adhering to the highest ethical standards and regulatory guidelines, ensuring the integrity and reliability of its research initiatives.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Istanbul, Bakırköy, Turkey
People applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
Discussion 0
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