Trials
Search / Trial NCT05641870

Molecular Profiling and Dynamic Changes of ctDNA in Unresectable Locally Advanced NSCLC

Launched by PARC DE SALUT MAR · Nov 29, 2022

Trial Information

Current as of January 14, 2025

Unknown status

Keywords

Liquid Biopsy Ct Dna Chemoradiotherapy

ClinConnect Summary

This clinical trial is studying a type of blood test called ctDNA (circulating tumor DNA) to see how well it can help doctors monitor the effectiveness of treatments for patients with locally advanced lung cancer that cannot be surgically removed. The trial is focused on patients who are receiving a combination of radiation therapy and chemotherapy, with some also getting a drug called durvalumab to help boost their immune response. By tracking ctDNA levels, researchers hope to predict how well the treatments are working and if the cancer might come back after treatment.

To be eligible for this study, patients must be at least 18 years old and have a confirmed diagnosis of unresectable locally advanced lung cancer. It's important that they are willing to participate in follow-up evaluations to assess their response to therapy. If someone is interested in joining the trial, they can expect to have regular blood tests and possibly benefit from close monitoring of their condition. The trial is currently recruiting participants of all genders, and it aims to gather valuable information that could improve future treatments for lung cancer.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Patients with newly diagnosed, histologically confirmed, unresectable locally advanced NSCLC.
  • ≥18 years of age.
  • Ability to understand the written informed consent and willingness to sign it.
  • Exclusion Criteria:
  • Patients who are unwilling to follow-up evaluation of response to therapy.
  • Any condition that, in the opinion of the investigator, would interfere with study results.

Trial Officials

Edurne Arriola

Principal Investigator

Parc de Salut Mar

About Parc De Salut Mar

Parc de Salut Mar is a leading healthcare institution located in Barcelona, Spain, dedicated to advancing medical research and improving patient outcomes through innovative clinical trials. As a prominent sponsor, it focuses on a wide range of therapeutic areas, emphasizing collaboration between multidisciplinary teams of healthcare professionals and researchers. The institution is committed to adhering to the highest ethical standards and regulatory guidelines, ensuring the safety and well-being of participants while contributing to the development of cutting-edge treatments and therapies. With state-of-the-art facilities and a strong emphasis on patient-centered care, Parc de Salut Mar plays a vital role in the evolving landscape of clinical research.

Locations

Barcelona, , Spain

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0

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