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Search / Trial NCT05643066

Esketamine-propofol Versus Propofol for Flexible Bronchoscopy

Launched by FUJIAN PROVINCIAL HOSPITAL · Dec 1, 2022

Trial Information

Current as of January 17, 2025

Completed

Keywords

Bronchoscopy Esketamine Procedure Sedation Propofol

ClinConnect Summary

Bronchoscopy is one of the most common procedures to detect lung and bronchus disease. The procedure is generally uncomfortable and associated with a relatively high risk of hypoxemia, coughing, wheezing, and dyspnea. Therefore, physicians are placing increasing importance on the use of procedure sedation due to the demand for comfortable medical care.

Propofol is an effective agent for sedation in bronchoscopy with rapid onset and recovery. However, the safety endpoints of propofol are not cost-effective, including injection pain, hypotension, apnea, airway compromise, and without a rever...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • 1. American Society of Anesthesiologists (ASA) classification I-III;
  • 2. Scheduled for ambulatory bronchoscopy.
  • Exclusion Criteria:
  • 1. Allergic or contraindications to studying drugs
  • 2. History of obstructive sleep apnea-hypopnea syndrome
  • 3. History of psychiatric illness
  • 4. History of neurological disease
  • 5. Pre-existing memory or cognitive impairment
  • 6. History of seizure disorders
  • 7. Pregnancy
  • 8. Substance abuse or intake of drugs that affect the central nervous system
  • 9. Inability to communicate in Mandarin Chinese.
  • 10. Illiteracy

Trial Officials

Xiaochun Zheng, MD

Study Chair

Fujian Provincial Hospital

About Fujian Provincial Hospital

Fujian Provincial Hospital is a leading medical institution in Fujian Province, China, renowned for its commitment to advancing healthcare through innovative research and clinical trials. As a prominent sponsor of clinical studies, the hospital integrates cutting-edge medical technology and multidisciplinary expertise to enhance patient care and contribute to the global medical community. With a focus on improving treatment outcomes across various specialties, Fujian Provincial Hospital adheres to the highest ethical standards and regulatory guidelines, ensuring the safety and well-being of participants while fostering advancements in medical science.

Locations

Fuzhou, Fujian, China

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0

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