Esketamine-propofol Versus Propofol for Flexible Bronchoscopy

Launched by FUJIAN PROVINCIAL HOSPITAL · Dec 1, 2022

Keywords

ClinConnect Summary

Bronchoscopy is one of the most common procedures to detect lung and bronchus disease. The procedure is generally uncomfortable and associated with a relatively high risk of hypoxemia, coughing, wheezing, and dyspnea. Therefore, physicians are placing increasing importance on the use of procedure sedation due to the demand for comfortable medical care.

Propofol is an effective agent for sedation in bronchoscopy with rapid onset and recovery. However, the safety endpoints of propofol are not cost-effective, including injection pain, hypotension, apnea, airway compromise, and without a rever...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. American Society of Anesthesiologists (ASA) classification I-III;
• • 2. Scheduled for ambulatory bronchoscopy.
• Exclusion Criteria:
• • 1. Allergic or contraindications to studying drugs
• • 2. History of obstructive sleep apnea-hypopnea syndrome
• • 3. History of psychiatric illness
• • 4. History of neurological disease
• • 5. Pre-existing memory or cognitive impairment
• • 6. History of seizure disorders
• • 7. Pregnancy
• • 8. Substance abuse or intake of drugs that affect the central nervous system
• • 9. Inability to communicate in Mandarin Chinese.
• • 10. Illiteracy

Trial Officials