Trials
Search / Trial NCT05644405

Stroke Volume Variations and Pulse Pressure Variations Undergoing Artificial Pneumothorax Surgery

Launched by CHINESE PLA GENERAL HOSPITAL · Dec 8, 2022

Trial Information

Current as of January 21, 2025

Completed

Keywords

ClinConnect Summary

Backgroud: This study aims to evaluate the ability of stroke volume variation (SVV) and pulse pressure variation (PPV) to predict fluid responsiveness in mechanically ventilated participants with artificial Pneumothorax during esophageal surgery.

Methods: 40 participants, diagnosed with esophageal cancer, undergoing thoracoscopic radical resection of esophageal cancer were studied. All the participants used Vigileo/FloTrac system for analysis. Haemodynamic data such as MAP, HR, SV, SVI, CO, CI, SVV, PPV were recorded before and after volume expansion (VE). Fluid responsiveness was defined ...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Must be arranged for thoracoscopic surgical treatment of esophageal cancer Must be mechanically ventilated with artificial Pneumothorax during the operation Must be normal in Allen test.
  • Exclusion Criteria:
  • Hypertension Coronary heart disease Arrhythmia Left ventricle ejection fractions \< 50% (EF\<50%) Pulmonary hypertension Congenital cardiovascular malformation Peripheral vascular disease Long-term history of oral vasoactive drugs

Trial Officials

Mi Weidong, Doctor

Study Chair

Chinese PLA General Hospital

About Chinese Pla General Hospital

The Chinese PLA General Hospital, a prominent military medical institution in Beijing, serves as a leading sponsor for clinical trials, focusing on advancing healthcare through innovative research and development. Renowned for its comprehensive medical services and cutting-edge research capabilities, the hospital is committed to improving patient outcomes through rigorous scientific investigation and collaboration with various stakeholders in the healthcare sector. With a multidisciplinary approach and a strong emphasis on evidence-based practices, the Chinese PLA General Hospital aims to contribute significantly to the global medical community by facilitating the development of safe and effective therapeutic interventions.

Locations

Beijing, Beijing, China

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0

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