Trials
Search / Trial NCT05644418

EIT During FCV in the Intensive Care Unit

Launched by ERASMUS MEDICAL CENTER · Dec 1, 2022

Trial Information

Current as of January 21, 2025

Completed

Keywords

Fcv Eit Mechanical Power Minute Volume Dissipated Energy Icu

ClinConnect Summary

No description provided

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • 18 years or older;
  • Informed consent form signed by the subject or a legal representative;
  • Controlled mechanical ventilation via an endotracheal tube -
  • FiO2 ≤50% and PEEP 10 cmH2O or lower
  • Exclusion Criteria:
  • Severe sputum stasis or production requiring frequent bronchial suctioning (more than 5 times per nurse shift)
  • Severe respiratory insufficiency defined as a PaO2 to FiO2 ratio of \<100mmHg or moderate to severe ARDS according to the Berlin definition of ARDS
  • Untreated pneumothorax (i.e. no pleural drainage)
  • Hemodynamic instability defined as a mean arterial pressure below 60mmHg not responding to fluids and/or vasopressors or a noradrenalin dose \>0.4mg/kg/min
  • Excessive subcutaneous emphysema (prevents proper functioning of the EIT device)
  • Thoracic wounds, bandages or other obstruction which prevent proper functioning of the EIT device
  • High (\>15 mmHg) or instable (an increase in sedation or osmotherapy is required) intracranial pressure
  • An inner tube diameter of 6mm or less

Trial Officials

Henrik Endeman, MD, PhD

Principal Investigator

Erasmus MC, Rotterdam

About Erasmus Medical Center

Erasmus Medical Center, located in Rotterdam, Netherlands, is a leading academic medical center renowned for its commitment to advancing healthcare through innovative research and clinical trials. As a prominent institution within the Erasmus University Rotterdam, the center integrates cutting-edge scientific inquiry with comprehensive patient care, focusing on a wide range of medical specialties. With a strong emphasis on multidisciplinary collaboration, Erasmus Medical Center aims to translate research findings into tangible clinical applications, enhancing treatment options and improving patient outcomes. The institution is dedicated to conducting ethical and rigorous clinical trials that contribute to the global body of medical knowledge and foster advancements in personalized medicine.

Locations

Rotterdam, Zuid Holland, Netherlands

Rotterdam, South Holland, Netherlands

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0

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