The Prognostic Value of 18F-PFPN PET Imaging in Patients With Malignant Melanoma

Launched by WUHAN UNION HOSPITAL, CHINA · Dec 2, 2022

Keywords

ClinConnect Summary

Melanoma is an aggressive malignancy with a high mortality rate. Accurate diagnosis and prognostic risk assessment are essential to the clinical management of melanoma. Melanin is present in most melanoma and has become a potential target for melanoma. This team has successfully synthesized a positron nuclide targeting melanin probe named 18F-PFPN (18F-N-(2-diethylaminoethyl)-4-(2-\[2-ethoxy\]-ethoxy) pyridine), which has been proven to be safe and well-tolerated. It has shown excellent diagnostic value in both primary and metastatic melanoma. This prospective study was designed to further ...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients with histopathologically confirmed melanoma;
• • Patients with complete clinical and follow-up data (including TNM stage, subtypes, and treatment strategies).
• Exclusion Criteria:
• • Uncertain histopathology;
• • A history of other malignancies.

Trial Officials